Protein Alignment Spn28F and SERPINA2

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 100/375 - (26%)
• Similarity: 178/375 - (47%)
• Gaps: 32/375 - (8%)

  Fly    18 ADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMR-----NVLKLPDDKKEVAAKY 77
            |.|.|:.||..:..:|::.:|.||.:|.:|..:|.:|.|..|:.     |:.:.|:.|  :...:
Human    61 AFDLYKELADLSQTSNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLTETPEAK--IHECF 123

  Fly    78 KDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIVNNWV 142
            :.:|..|...:....|:..:.::|||..:||.::.:..|..:.:||.:|:..|..:|...:||:|
Human   124 QQVLQALSRPDTRLQLTTGSSLFVNKSMKLVDTFLEDTKKLYHSEASSINFRDTEEAKEQINNYV 188

  Fly   143 DNQTRGKIKDLVS--SNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSL 205
            :.:|..|:.|||.  ..|.|   |.:::.|.|.|:|:.||..:......|.|.|:..:.|.|::.
Human   189 EKRTGRKVVDLVKHLKKDTS---LALVDYISFHGKWKDKFKAEHIMVEGFHVDDKTIIRVPMINH 250

  Fly   206 FQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIV-----GFKPKLSKMDVTL 265
            ...|....|.||.:.::...|..::.:..| |||. ..:.:||:|:.     ..:.......:.|
Human   251 LGRFDIHRDRELSSWVLAQHYVGNATAFFI-LPDP-KKMWQLEEKLTYSHLENIQRAFDIRSINL 313

  Fly   266 RLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAAT 330
            ..||..|....:|.:||..:||...|...||...:.:.:.:.:.|.:|.|.:.::|:|.||..|.
Human   314 HFPKLSISGTYKLKRVLRNLGITKIFSNEADLSGVSQEAPLKLSKAVHVAVLTIDEKGTEATGAP 378

  Fly   331 AL---LFVRYSMPMPSSQMVFNADHPFAYVIRDRETIY--FQGHFVKPNE 375
            .|   .:.:|...|      ||  .||..:|:|..|.:  |.|..|.|.:
Human   379 HLEEKAWSKYQTVM------FN--RPFLVIIKDDITNFPLFIGKVVNPTQ 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	99/371 (27%)
SERPINA2	NP_006211.2	serpinA2_PIL	56..418	CDD:381018	99/371 (27%)