Protein Alignment Spn28F and SERPINA2

DIOPT Version :9

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 100/375 - (26%)
• Similarity: 178/375 - (47%)
• Gaps: 32/375 - (8%)

  Fly    18 ADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMR-----NVLKLPDDKKEVAAKY 77
            |.|.|:.||..:..:|::.:|.||.:|.:|..:|.:|.|..|:.     |:.:.|:.|  :...:
Human    61 AFDLYKELADLSQTSNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLTETPEAK--IHECF 123

  Fly    78 KDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIVNNWV 142
            :.:|..|...:....|:..:.::|||..:||.::.:..|..:.:||.:|:..|..:|...:||:|
Human   124 QQVLQALSRPDTRLQLTTGSSLFVNKSMKLVDTFLEDTKKLYHSEASSINFRDTEEAKEQINNYV 188

  Fly   143 DNQTRGKIKDLVS--SNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSL 205
            :.:|..|:.|||.  ..|.|   |.:::.|.|.|:|:.||..:......|.|.|:..:.|.|::.
Human   189 EKRTGRKVVDLVKHLKKDTS---LALVDYISFHGKWKDKFKAEHIMVEGFHVDDKTIIRVPMINH 250

  Fly   206 FQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIV-----GFKPKLSKMDVTL 265
            ...|....|.||.:.::...|..::.:..| |||. ..:.:||:|:.     ..:.......:.|
Human   251 LGRFDIHRDRELSSWVLAQHYVGNATAFFI-LPDP-KKMWQLEEKLTYSHLENIQRAFDIRSINL 313

  Fly   266 RLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAAT 330
            ..||..|....:|.:||..:||...|...||...:.:.:.:.:.|.:|.|.:.::|:|.||..|.
Human   314 HFPKLSISGTYKLKRVLRNLGITKIFSNEADLSGVSQEAPLKLSKAVHVAVLTIDEKGTEATGAP 378

  Fly   331 AL---LFVRYSMPMPSSQMVFNADHPFAYVIRDRETIY--FQGHFVKPNE 375
            .|   .:.:|...|      ||  .||..:|:|..|.:  |.|..|.|.:
Human   379 HLEEKAWSKYQTVM------FN--RPFLVIIKDDITNFPLFIGKVVNPTQ 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	98/368 (27%)
SERPINA2	NP_006211.2	SERPIN	62..418	CDD:214513	98/370 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010