DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28F and Serpina7

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_808588.3	Gene:	Serpina7 / 331535	MGIID:	3041197	Length:	426	Species:	Mus musculus

Alignment Length:	376	Identity:	101/376 - (26%)
Similarity:	182/376 - (48%)	Gaps:	17/376 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVL--KLPDDK-KEV 73
            |::..||...|:.|:.||...|:..||:|:.:||:|...|:.:.|..::..||  .|.|.. .|:
Mouse    55 SINADFAFSLYRRLSVENPDLNIFFSPVSISVALAMLSFGSGSSTQTQILEVLGFNLTDTPVTEL 119

  Fly    74 AAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIV 138
            ...::.|:..|...:....|.:.|.:::.::.:.:..:...||..:..|..:.|..:.:.|...:
Mouse   120 QQGFQHLICSLNFPKNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQHKI 184

  Fly   139 NNWVDNQTRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFN-PKLTKKRNFRVSDQKSVPVEM 202
            |::|:.||:|||..|:....:: :.:|::|.|:|:.||...|. .|..:..||.|....:|.|.|
Mouse   185 NSYVEKQTKGKIVGLIQGLKLN-IIMILVNYIHFRAQWANPFRVSKTEESSNFSVDKSTTVQVPM 248

  Fly   203 MSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSE------LEKKIVGFKPKLSKM 261
            |...:.:....|.||...::::.|..::|::.: ||.  :|..|      ..|.:..:...|.|.
Mouse   249 MHQLEQYYHYVDMELNCTVLQMDYSENALALFV-LPK--EGHMEWVEAAMSSKTLKKWNYLLQKG 310

  Fly   262 DVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEA 326
            .|.|.:|||.|.....|...|..||::|||.:||||..:.|:|.:.:....|||.:.:.|||.:.
Mouse   311 WVELFVPKFSISATYDLGSTLQKMGMRDAFAESADFPGITEDSGLKLSYAFHKAVLHIGEEGTKE 375

  Fly   327 AAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKPNE 375
            .|:..:..:. ...:|....|...|..|..:|.::.|  :.|.|..|.|.:
Mouse   376 GASPEVGSLD-QQEVPPLHPVIRLDRAFLLMILEKRTRSVLFLGKLVNPTK 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	98/367 (27%)
Serpina7	NP_808588.3	alpha-1-antitrypsin_like	57..419	CDD:239011	97/366 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010