Protein Alignment Spn28F and SERPINA9

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_783866.3
• Gene: SERPINA9 / 327657
• HGNCID: 15995
• Length: 417
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 111/378 - (29%)
• Similarity: 197/378 - (52%)
• Gaps: 21/378 - (5%)

  Fly    12 SVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMR-----NVLKLPDDKK 71
            |::..||...|:.|..|..:.|:..||:||..:|:|..:||.:.|..::.     |:...|:  .
Human    46 SLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPE--S 108

  Fly    72 EVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASS 136
            .:...::.|:..|....|..||.:.:.::|.|:.||..::...||..:.||..:.|..:|:.|.:
Human   109 AIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQA 173

  Fly   137 IVNNWVDNQTRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKR-NFRVSDQKSVPV 200
            .:|:.|..:|:||:.|::...|: ...::::|.|:||.:||..|:|:.|:|. .|.|.:|.:|.|
Human   174 RINSHVKKKTQGKVVDIIQGLDL-LTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHV 237

  Fly   201 EMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIVG-----FKPKLSK 260
            .||...:.|....|:||...::::.|:..:::..: ||.: ..:.:||:.:..     :...|.|
Human   238 PMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFV-LPSK-GKMRQLEQALSARTLRKWSHSLQK 300

  Fly   261 MDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAE 325
            ..:.:.:|:|.|.....|..:|..||||:.|:|:|||..:.:..::.|.|..|||.::|:|||.|
Human   301 RWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTE 365

  Fly   326 AAAATALLFVRYSMPMPSSQMV-FNADHPFAYVIRDRET--IYFQGHFVKPNE 375
            |.|||...|:..|...||...| ||  ..|..:|.::.|  |.|.|....|.:
Human   366 ATAATTTKFIVRSKDGPSYFTVSFN--RTFLMMITNKATDGILFLGKVENPTK 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	110/374 (29%)
SERPINA9	NP_783866.3	serpinA9_centerin	30..417	CDD:381024	111/378 (29%)