DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28F and Serpinc1

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_001012027.1	Gene:	Serpinc1 / 304917	RGDID:	1307404	Length:	465	Species:	Rattus norvegicus

Alignment Length:	386	Identity:	120/386 - (31%)
Similarity:	210/386 - (54%)	Gaps:	31/386 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TSVSCRFADDFYQLLA-KENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKKEVA 74
            :..:.|||.:|||.|| .:|..:|:..||||:..|.:|..:||...|.:::..|.|.....::.:
  Rat    85 SKANSRFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNNTLKQLMEVFKFDTISEKTS 149

  Fly    75 AKYKDLLSKLEGR-----EKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVD-PNK 133
            .:.....:||..|     .|.:.|..|||::.:|......||..:.:..:.|:.:.:|..: |.:
  Rat   150 DQIHFFFAKLNCRLYRKANKSSNLVSANRLFGDKSLTFNESYQDVSEIVYGAKLQPLDFKENPEQ 214

  Fly   134 ASSIVNNWVDNQTRGKIKDLVSSNDMSKM-ELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKS 197
            :...:||||.|:|.|:|||::....:.:: .|:::|.|||||.|:.||:|:.|:|..|...|.:|
  Rat   215 SRVTINNWVANKTEGRIKDVIPQGAIDELTALVLVNTIYFKGLWKSKFSPENTRKEPFHKVDGQS 279

  Fly   198 VPVEMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIV-----GFKPK 257
            ..|.||.....|:.....| |.:::|:|::...::|::.||.....|:::|:::.     .:..:
  Rat   280 CLVPMMYQEGKFKYRRVGE-GTQVLEMPFKGDDITMVLILPKPEKSLAKVEQELTPELLQEWLDE 343

  Fly   258 LSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAF--EKS------ADFKDLVENSNVHVKKVIHK 314
            ||::.:.:.:|:|:||....|.:.|..||:.|.|  |||      |:.:|     ::.|....||
  Rat   344 LSEVMLVVHVPRFRIEDSFSLKEQLQDMGLVDLFSPEKSQLPGIIAEGRD-----DLFVSDAFHK 403

  Fly   315 AFIEVNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRD--RETIYFQGHFVKP 373
            ||:||||||:||||:|:::....|  :..|::.|.|:.||..:||:  ..||.|.|....|
  Rat   404 AFLEVNEEGSEAAASTSVVITGRS--LNPSRVTFKANRPFLVLIREVALNTIIFMGRVSNP 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	119/378 (31%)
Serpinc1	NP_001012027.1	antithrombin-III_like	80..459	CDD:239000	119/381 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930