Protein Alignment Spn28F and Serpinb12

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001129339.1
• Gene: Serpinb12 / 304692
• RGDID: 1566382
• Length: 421
• Species: Rattus norvegicus
• Alignment Length: 415
• Identity: 134/415 - (32%)
• Similarity: 217/415 - (52%)
• Gaps: 60/415 - (14%)

  Fly    16 RFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVL---KLPDDKK----EV 73
            :|..||:|.::|::|..|:...|||:..|..|..:|||..:||::..||   :||.|::    |.
  Rat    10 KFCFDFFQEISKDDAHKNIFVCPLSLSAAFGMVRLGARGDSAQQIDEVLHFNELPKDERKEPSEP 74

  Fly    74 AAKYKDLLSKLEGREKVA----------------------------------TLSLANRIYVNKK 104
            ::|.|...|.|||:::..                                  |||:|||:|..::
  Rat    75 SSKSKASDSSLEGQKQTTASQGQQGESTNEHRLLGCHFGKLLSRIDRDKAHYTLSMANRLYGEQE 139

  Fly   105 FQLVPSYNQMVKDSFMAEAEAIDI-VDPNKASSIVNNWVDNQTRGKIKDLVSSNDMSKMELIVL- 167
            |.:.|.|:..:.:.:....|::|. .|..|:...:|.||::|::||||:|.....:....::||
  Rat   140 FPICPEYSDDITEFYHTTIESVDFQKDTEKSREEINFWVESQSQGKIKELFDKEAIDNSTVLVLV 204

  Fly   168 NAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQSFRAAHDSELGAKIIELPYRNSSLS 232
            ||:|||.:||.:|:.:.|....|.:|:.:...|:||:....||.....||.|:|:|:.|....||
  Rat   205 NAVYFKAKWEKEFDSENTVDAPFCLSENEKKTVKMMNQKGQFRIGFIEELQAQILEMKYTTGKLS 269

  Fly   233 MLIFLP----DQVDGLSELEKKIVGFK-------PKLSKMDVTLRLPKFKIEFFAQLNKVLVAMG 286
            ||:.||    |.|..|.||||||...|       ..:|:..|.:..|:|.:|....||.||..||
  Rat   270 MLVLLPSSSEDNVKSLQELEKKINHEKLLAWSNPENMSEKPVAISFPQFIMEDSYDLNSVLQDMG 334

  Fly   287 IQDAFE-KSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAATALLFVRYSMPMPSSQMVFNA 350
            |:|.|: ..||...:.::.::|:.||:||.|:||:|.|.:||||:..:....::|   |::.|||
  Rat   335 IRDVFDGTKADLTGISKSPSLHLSKVVHKTFVEVDEMGTQAAAASGAVVAEKALP---SRVEFNA 396

  Fly   351 DHPFAYVIRDR--ETIYFQGHFVKP 373
            :.||.:.||..  :::.|.|....|
  Rat   397 NRPFLFFIRHNGTQSLLFCGRVYSP 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	133/413 (32%)
Serpinb12	NP_001129339.1	serpinB12_yukopin	1..421	CDD:381037	133/413 (32%)