Protein Alignment Spn28F and Serpine2

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_062070.1
• Gene: Serpine2 / 29366
• RGDID: 3748
• Length: 397
• Species: Rattus norvegicus
• Alignment Length: 384
• Identity: 122/384 - (31%)
• Similarity: 187/384 - (48%)
• Gaps: 56/384 - (14%)

  Fly    21 FYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKL----------PDDKKEVAA 75
            |.|:: |.....|::.||..:...|.|..:||..:|.:::..|::.          ..:|..|:.
  Rat    39 FNQII-KSQPHENVVISPHGIASILGMLQLGADGRTKKQLSTVMRYNVNGVGKVLKKINKAIVSK 102

  Fly    76 KYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIVNN 140
            |.||:            :::||.::|...|::...:....|:.|..|.::::..||..|...:|.
  Rat   103 KNKDI------------VTVANAVFVRNGFKVEVPFAARNKEVFQCEVQSVNFQDPASACDAINF 155

  Fly   141 WVDNQTRGKIKDLVSSN--DMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEM- 202
            ||.|:|||.|.:|:|.|  |.:..:|:::||:||||.|:.:|.|:.||||.|...|.||..|.|
  Rat   156 WVKNETRGMIDNLLSPNLIDSALTKLVLVNAVYFKGLWKSRFQPENTKKRTFVAGDGKSYQVPML 220

  Fly   203 --MSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIVGFKPKLSKMDVT- 264
              :|:|:|......:.|....|||||...|:||||.||      :|....:....|.:|...:.
  Rat   221 AQLSVFRSGSTKTPNGLWYNFIELPYHGESISMLIALP------TESSTPLSAIIPHISTKTINS 279

  Fly   265 -----------LRLPKFKIEFFAQLNKVLVAMGIQDAFEKS-ADFKDLVENSNVHVKKVIHKAFI 317
                       |.||||.......|.:.|.|:||.:.||.| |:|..:..:.::||..::.||.|
  Rat   280 WMNTMVPKRMQLVLPKFTAVAQTDLKEPLKALGITEMFEPSKANFAKITRSESLHVSHILQKAKI 344

  Fly   318 EVNEEGAEAA-AATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373
            ||:|:|.:|| ..||:|..|.|.|.      |..|.||.:.||...|  |.|.|...||
  Rat   345 EVSEDGTKAAVVTTAILIARSSPPW------FIVDRPFLFCIRHNPTGAILFLGQVNKP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	120/382 (31%)
Serpine2	NP_062070.1	serpinE2_GDN	21..395	CDD:381039	120/380 (32%)