Protein Alignment Spn28F and Serpinb1b

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_766640.1
• Gene: Serpinb1b / 282663
• MGIID: 2445361
• Length: 382
• Species: Mus musculus
• Alignment Length: 379
• Identity: 120/379 - (31%)
• Similarity: 207/379 - (54%)
• Gaps: 17/379 - (4%)

  Fly    11 TSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKKEVAA 75
            :|.:..|..:.:..|.:.:...|:..||.|:..:|:|.::||:..||.::...|.. |..:::.:
Mouse     5 SSANTLFTLELFHTLKESSPTGNIFFSPFSISSSLAMVFLGAKGSTAAQLSKTLHF-DSVEDIHS 68

  Fly    76 KYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNK-ASSIVN 139
            .::.|.:::.......||.||||:|..|.:..:|.:....:..:.|:..|:|....:: |...:|
Mouse    69 CFQSLTAEVSKLGASHTLKLANRLYGEKTYNFLPEFLASTQKMYSADLAAVDFQHASEDARKEIN 133

  Fly   140 NWVDNQTRGKIKDLVSSNDMSKM-ELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMM 203
            .||..||.|||.:|::...:..| :|:::|||||||.||.:|..:.|....||::.:.:..|:||
Mouse   134 QWVKGQTEGKIPELLAKGVVDSMTKLVLVNAIYFKGIWEEQFMTRETINAPFRLNKKDTKTVKMM 198

  Fly   204 SLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVD----GLSELEKKIVGFK-------PK 257
            ...:.|...:.|:|..|::|:||:...|||:|.||:.::    ||.::|:::...|       ..
Mouse   199 YQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLKKIEEQLTLGKLHEWTKHEN 263

  Fly   258 LSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEK-SADFKDLVENSNVHVKKVIHKAFIEVNE 321
            |..:||.::||:||:|....||..|..:|:||.|.. .||...:..:.::.|.|::||:|::|||
Mouse   264 LRNIDVHVKLPRFKMEESYILNSNLCCLGVQDLFSSGKADLSGMSGSRDLFVSKIVHKSFVDVNE 328

  Fly   322 EGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373
            :|.||||||..:.......||:.|.||..||||.:.||...|  :.|.|....|
Mouse   329 QGTEAAAATGGIIQVLCEKMPTPQEVFTVDHPFLFFIRHNPTANMIFFGRVCSP 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	119/376 (32%)
Serpinb1b	NP_766640.1	serpinB1_LEI	1..382	CDD:381028	119/377 (32%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	352..382		12/29 (41%)