Protein Alignment Spn28F and Serpina3b

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_766612.1
• Gene: Serpina3b / 271047
• MGIID: 2182835
• Length: 420
• Species: Mus musculus
• Alignment Length: 390
• Identity: 111/390 - (28%)
• Similarity: 189/390 - (48%)
• Gaps: 26/390 - (6%)

  Fly     2 KHLCLLLLATSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKL 66
            |.|..|.|| |::..||..||:.||.:|...|:..||..:..||:...:||:..|.:|:..|||.
Mouse    40 KQLDSLTLA-SINTDFAFSFYKELALKNPHKNIAFSPFGIATALNSLTLGAKGNTLEEILEVLKF 103

  Fly    67 ---PDDKKEVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDI 128
               ...:.::...:|.||.:|........:...|.::|.|..|::..:.:..:..:..|....:.
Mouse   104 NLTETSEADIHQGFKHLLQRLSHPGDQVQIRTGNALFVEKHLQILAEFKEKARALYHTEVFTANF 168

  Fly   129 VDPNKASSIVNNWVDNQTRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVS 193
            ..|::|..::|:::.|||:||||:|||..| ....::::|.::||.:|...||...|....|.|.
Mouse   169 QQPHEAMKLINSYMSNQTQGKIKELVSDMD-GNTSMVIVNDLFFKAEWMVPFNSDDTFMGKFIVD 232

  Fly   194 DQKSVPVEMMSLFQSFRAAH--DSELGAKIIELPYRNSSLSMLIFLPD-----QVDGLSE---LE 248
            ..:.|.|.||.. ::.|..:  |.||...::||.|:.:..:|.| |||     ||:...:   |:
Mouse   233 RSRHVKVPMMKT-KNLRTPYFRDEELKCTVVELNYKGNGKAMFI-LPDQGKMQQVEASLQPGTLK 295

  Fly   249 KKIVGFKPKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIH 313
            |.....:|:..|   .|.||||.:.....|..:|..:||::.|...||...:....|:.|.::||
Mouse   296 KWRKSLRPRKIK---ELHLPKFSLSQHYNLEDILPELGIRELFSTQADLSGITGVKNITVSEMIH 357

  Fly   314 KAFIEVNEEGAEAAAATALLFVRYSMPMPSSQMVF-NADHPFAYVIRDRET--IYFQGHFVKPNE 375
            ...:::.|:|.|..|.|   .|.|:......:.|| ..:..|.|::.|:..  |:..|..:.|:|
Mouse   358 STELDMTEKGTEGDAIT---IVGYNFMSAKLKPVFVKFEDQFLYIVLDQGDLWIHVMGKVINPSE 419

  Fly   376  375
            Mouse   420  419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	104/376 (28%)
Serpina3b	NP_766612.1	serpinA3_A1AC	37..418	CDD:381019	109/387 (28%)
		RCL	367..392		8/27 (30%)