Protein Alignment Spn28F and SERPINA11

DIOPT Version :9

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 103/385 - (26%)
• Similarity: 188/385 - (48%)
• Gaps: 38/385 - (9%)

  Fly    11 TSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMR-----NVLKLPDDK 70
            |.....||...|:.||.: |..|:..||:|:...|::..:||:|.|:..:.     |:.:.|:
Human    51 TPTITNFALRLYKELAAD-APGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPE-- 112

  Fly    71 KEVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKAS 135
            .::...::.||..|........|.:.|.::::|:.:....|...:|:.:.|.|.:.:..|.....
Human   113 ADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTG 177

  Fly   136 SIVNNWVDNQTRGKIKDLVSSNDMSKMELIVL-NAIYFKGQWEYKFNPKLTKKR-NFRVSDQKSV 198
            ..:|:::..||.|::.|.:.  :.|:...:|| |.|:||.:|::.|:...|:|: :|.|.::.|:
Human   178 RQINDYLRRQTYGQVVDCLP--EFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSL 240

  Fly   199 PVEMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPD-----QVDGLSE---LEKKIVGFK 255
            .|.||...:..|..:|.:|...::::.||.::|::|: |||     ||:...:   |.|......
Human   241 QVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV-LPDPGKMKQVEAALQPQTLRKWGQLLL 304

  Fly   256 PKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVN 320
            |.|    :.|.||:|.|.....|..:|..:|:.:.....|||..:....|..:.||.|||.::::
Human   305 PSL----LDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMS 365

  Fly   321 EEGAEAAAATALLFVRYSMP-----MPSSQMVFNADHPFAYVIRD--RETIYFQGHFVKP 373
            |:|.||.||:.||    |.|     |......||  .||..::.:  .:::.|.|..|.|
Human   366 EKGTEAGAASGLL----SQPPSLNTMSDPHAHFN--RPFLLLLWEVTTQSLLFLGKVVNP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	100/377 (27%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	100/378 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010