Protein Alignment Spn28F and Serpina1

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001421270.1
• Gene: Serpina1 / 24648
• RGDID: 3326
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 372
• Identity: 106/372 - (28%)
• Similarity: 194/372 - (52%)
• Gaps: 28/372 - (7%)

  Fly    17 FADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMR-----NVLKLPDDKKEVAAK 76
            ||...|:.|..::..:|:..||:|:..|.:|..:|::..|.:::.     |:.::|:  .::...
  Rat    51 FAFSLYRELVHQSNTSNIFFSPMSITTAFAMLSLGSKGDTRKQILEGLEFNLTQIPE--ADIHKA 113

  Fly    77 YKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIVNNW 141
            :..||..|...:....|:..|.::|||..:||..:.:.||:::.:||.:::..|..:|..::|::
  Rat   114 FHHLLQTLNRPDSELQLNTGNGLFVNKNLKLVEKFLEEVKNNYHSEAFSVNFADSEEAKKVINDY 178

  Fly   142 VDNQTRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLF 206
            |:..|:|||.||:...|...:..:| |.|:|||:|:..|||:.|:..:|.|....:|.|.||:..
  Rat   179 VEKGTQGKIVDLMKQLDEDTVFALV-NYIFFKGKWKRPFNPEHTRDADFHVDKSTTVKVPMMNRL 242

  Fly   207 QSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDG-LSELEKKIVGFKPKLSKM-------DV 263
            ..|...:.|.|.:.::.:.|..::.::.: |||  || :..||:.:.  |..:|:.       ..
  Rat   243 GMFDMHYCSTLSSWVLMMDYLGNATAIFL-LPD--DGKMQHLEQTLT--KDLISRFLLNRQTRSA 302

  Fly   264 TLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAA 328
            .|..||..|.....|..:|.::||...|...||...:.|::.:.:.:.:|||.:.::|.|.|||.
  Rat   303 ILYFPKLSISGTYNLKTLLSSLGITRVFNNDADLSGITEDAPLKLSQAVHKAVLTLDERGTEAAG 367

  Fly   329 ATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373
            ||.:..|..|:|   .|:.|  ||||.::|.:.||  ..|.|..:.|
  Rat   368 ATVVEAVPMSLP---PQVKF--DHPFIFMIVESETQSPLFVGKVIDP 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	105/370 (28%)
Serpina1	NP_001421270.1	serpinA1_A1AT	44..411	CDD:381012	106/372 (28%)
		RCL	367..386		7/23 (30%)