DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28F and Serpinb8

DIOPT Version :9

Sequence 1:NP_524957.2 Gene:Spn28F / 49807 FlyBaseID:FBgn0028987 Length:375 Species:Drosophila melanogaster
Sequence 2:NP_035589.1 Gene:Serpinb8 / 20725 MGIID:894657 Length:374 Species:Mus musculus


Alignment Length:370 Identity:123/370 - (33%)
Similarity:199/370 - (53%) Gaps:19/370 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 FADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKKEVAAKYKDLL 81
            ||....::|::::.:.||...|:||..||:|.|:||:..||.:|..||.| ....:|...::.||
Mouse    11 FAISLLKILSEKDKSRNLFFCPMSVSSALAMVYLGAKGNTATQMSEVLGL-SGNGDVHQSFQTLL 74

  Fly    82 SKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIV-DPNKASSIVNNWVDNQ 145
            :::...:....|..|.|::..:....:.::.:.....:.|..|.:... |.......:|:||..:
Mouse    75 AEINKTDTQYLLKSACRLFGEESCDFLSTFKESCHKFYQAGLEELSFAKDTEGCRKHINDWVSEK 139

  Fly   146 TRGKIKDLVSSNDMSKM-ELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQSF 209
            |.|||.:::|...:..: :|:::||:||||:|:.:|:.|.|:...|:.:.:|.. |:||.....|
Mouse   140 TEGKISEVLSPGTVCPLTKLVLVNAMYFKGKWKAQFDRKYTRGMPFKTNQEKKT-VQMMFKHAKF 203

  Fly   210 RAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIVGFKPK-------LSKMDVTLRL 267
            :..|..|:..:::.|||....|||:|.|||:...|:.:||.:...|.:       |::..|.:.|
Mouse   204 KMGHVDEVNMQVLALPYAEEELSMVILLPDESTDLAVVEKALTYEKLRAWTNPETLTESQVQVFL 268

  Fly   268 PKFKIEFFAQLNKVLVAMGIQDAFEKS-ADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAATA 331
            |:.|:|....|..||..:|:.||||:: |||..:....||.|.||.||.|:||||||.|||||||
Mouse   269 PRLKLEESYDLETVLQNLGMTDAFEETRADFSGMTTKKNVPVSKVAHKCFVEVNEEGTEAAAATA 333

  Fly   332 LL-FVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373
            :: ..|.....|.    |.|||||.:.|...:|  |.|.|.|..|
Mouse   334 VIRNARCCRTEPR----FCADHPFLFFIWHHKTSSILFCGRFSSP 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28FNP_524957.2 SERPIN 14..370 CDD:238101 121/365 (33%)
Serpinb8NP_035589.1 SERPIN 4..374 CDD:294093 122/368 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
65.930

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