DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28F and Serpinb6a

DIOPT Version :9

Sequence 1:NP_524957.2 Gene:Spn28F / 49807 FlyBaseID:FBgn0028987 Length:375 Species:Drosophila melanogaster
Sequence 2:NP_001157589.1 Gene:Serpinb6a / 20719 MGIID:103123 Length:399 Species:Mus musculus


Alignment Length:375 Identity:139/375 - (37%)
Similarity:209/375 - (55%) Gaps:25/375 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 FADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDK------KEVAA 75
            ||.:..::|. |:::.|:..||:|:..||:|.:|||:..||.:|...|.|  ||      .:|..
Mouse    32 FALNLLKILG-EDSSKNVFLSPMSISSALAMVFMGAKGTTASQMAQALAL--DKCSGNGGGDVHQ 93

  Fly    76 KYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKAS-SIVN 139
            .::.||:::........|..|||::.:|...|:.|:.......:.||.|.:|.....:.| ..:|
Mouse    94 GFQSLLTEVNKTGTQYLLRTANRLFGDKTCDLLASFKDSCLKFYEAELEELDFQGATEESRQHIN 158

  Fly   140 NWVDNQTRGKIKDLVSSNDM-SKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMM 203
            .||..:|..|||:::|...: |...|:::|||||||.||.:||.:.|::..|:||..:..||:||
Mouse   159 TWVAKKTEDKIKEVLSPGTVNSDTSLVLVNAIYFKGNWEKQFNKEHTREMPFKVSKNEEKPVQMM 223

  Fly   204 SLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIVGFK----PKLSKMD-- 262
            ....:|:..:..|:..||:.|||.:|.|:|:|.|||:...||.:||::...|    .:|.|||  
Mouse   224 FKKSTFKMTYIGEIFTKILLLPYVSSELNMIIMLPDEHVELSTVEKEVTYEKFIEWTRLDKMDEE 288

  Fly   263 -VTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEA 326
             |.:.|||||:|....:|..|..:|:.|||...|||..:.....:.:.||:||||:||||||.||
Mouse   289 EVEVFLPKFKLEENYNMNDALYKLGMTDAFGGRADFSGMSSKQGLFLSKVVHKAFVEVNEEGTEA 353

  Fly   327 AAATA-LLFVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373
            ||||| ::.||.....|.    |.|||||.:.|...:|  |.|.|.|..|
Mouse   354 AAATAGMMTVRCMRFTPR----FCADHPFLFFIHHVKTNGILFCGRFSSP 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28FNP_524957.2 SERPIN 14..370 CDD:238101 137/370 (37%)
Serpinb6aNP_001157589.1 SERPIN 25..399 CDD:294093 138/373 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100128
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
76.830

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