DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28F and Serpina3m

DIOPT Version :9

Sequence 1:NP_524957.2 Gene:Spn28F / 49807 FlyBaseID:FBgn0028987 Length:375 Species:Drosophila melanogaster
Sequence 2:NP_033279.2 Gene:Serpina3m / 20717 MGIID:98378 Length:418 Species:Mus musculus


Alignment Length:377 Identity:115/377 - (30%)
Similarity:196/377 - (51%) Gaps:15/377 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LLATSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKL---PDD 69
            |...|::..||...|:.:|.:|...|::.||||:..||::..:||:..|.:|:...||.   ...
Mouse    45 LTLASINTDFAFSLYKKMALKNPDKNIVFSPLSISAALALVSLGAKGNTLEEILEGLKFNLTETS 109

  Fly    70 KKEVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKA 134
            :.::...:..||.:|...|....:::.|.:::.|..|::..:::..:..:..||...|...|.:|
Mouse   110 EADIHQGFGHLLQRLSQPEDQDQINIGNAMFIEKDLQILAEFHEKTRALYQTEAFTADFQQPTEA 174

  Fly   135 SSIVNNWVDNQTRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVP 199
            :.::|::|.|||:|.||.|:|..| .:..::::|.|||||:|:..|:|:.|.:..|.:.:::||.
Mouse   175 TKLINDYVSNQTQGMIKKLISELD-DRTLMVLVNYIYFKGKWKISFDPQDTFESEFYLDEKRSVK 238

  Fly   200 VEMMSL-FQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPD-----QVDGLSELEKKIVGFKPKL 258
            |.||.: |.:.|...|.||...::||.|..:: |.|..|||     ||:...:.|.....:|...
Mouse   239 VPMMKMKFLTTRHFRDEELSCSVLELKYTGNA-SALFILPDQGRMQQVEASLQPETLRKWWKSLK 302

  Fly   259 SKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEG 323
            ::....|.||||.|.....|..:|..:||::.|.|.||...:....::.|.:|:|||.::|.|.|
Mouse   303 TRKIGELYLPKFSISTDYNLKDILPELGIKEIFSKQADLSGITGTKDLSVSQVVHKAVLDVAETG 367

  Fly   324 AEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDR--ETIYFQGHFVKP 373
            .||||||..:|...|..:.:..:.||  .||..||...  :|..|......|
Mouse   368 TEAAAATGFIFGFRSRRLQTMTVQFN--RPFLMVISHTGVQTTLFMAKVTNP 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28FNP_524957.2 SERPIN 14..370 CDD:238101 112/366 (31%)
Serpina3mNP_033279.2 SERPIN 56..417 CDD:214513 110/364 (30%)
RCL 367..392 9/24 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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