DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28F and Serpinb6b

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_035584.1	Gene:	Serpinb6b / 20708	MGIID:	894688	Length:	377	Species:	Mus musculus

Alignment Length:	365	Identity:	134/365 - (36%)
Similarity:	202/365 - (55%)	Gaps:	27/365 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDK------KEVAAKYKDLLSKLEG 86
            |:::.|::.||:||..||:|.:|||:..||.:|...|.|  ||      ::|...::.||::...
Mouse    21 EDSSRNVLFSPISVSSALAMVFMGAKGTTASQMAQALSL--DKCSGKGGRDVHQGFQSLLTETNK 83

  Fly    87 REKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKAS-SIVNNWVDNQTRGKI 150
            ......|..|||::..|.|.::.|:....:..:.||.|.:|.....:.| ..:|.||..:|..||
Mouse    84 TGTQYVLRTANRLFGEKTFDILASFKDSCRKFYEAEMEELDFKGATEQSRQHINAWVAKKTEDKI 148

  Fly   151 KDLVSSNDM-SKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQSFRAAHD 214
            .:|:||..: |...|:::|||||||.||.:||.:.|::..|.|:.....||:||....:|:..:.
Mouse   149 TELLSSGSVNSNTPLVLVNAIYFKGNWEKQFNKEDTQEMPFNVTKDVVKPVQMMFQKSTFKMTYV 213

  Fly   215 SELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIVGFK----PKLSKM---DVTLRLPKFKI 272
            .|:...|:.|||..:.|:|:|.|||:...||.:||:|...|    .:|.||   :|.:.|||||:
Mouse   214 EEISTNILLLPYVGNELNMIIMLPDEHIELSMVEKEITYKKFIEWTRLDKMEEEEVEVFLPKFKL 278

  Fly   273 EFFAQLNKVLVAMGIQDAFEKS-ADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAATAL-LFV 335
            |....:..||..:|:.||||:. |||..:.....:.:.|||||:|:||||||.|||||||. :..
Mouse   279 EENYDMKDVLCRLGMTDAFEEGMADFSGIASKEGLFLSKVIHKSFVEVNEEGTEAAAATAANIGF 343

  Fly   336 RYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373
            |..:|      .|.|:|||.:.|:...|  |.|.|.|..|
Mouse   344 RCMVP------YFCANHPFLFFIQHSRTSGIVFCGRFSSP 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	132/360 (37%)
Serpinb6b	NP_035584.1	serpin	1..377	CDD:393296	133/363 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.830