DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn28F and Serpinf2

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_032904.1	Gene:	Serpinf2 / 18816	MGIID:	107173	Length:	491	Species:	Mus musculus

Alignment Length:	383	Identity:	112/383 - (29%)
Similarity:	185/383 - (48%)	Gaps:	59/383 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKKEVAAKYKDLL 81
            |..|.:.|:|:.:.::||:.|||||.:|||...:||:.:|...:..||.:     ...:....||
Mouse    89 FTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHM-----NTGSCLPHLL 148

  Fly    82 SKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKAS-------SIVN 139
            |.........|:.||.|||:.|.|.        :||.|:.::|.:....|.|.:       :.:|
Mouse   149 SHFYQNLGPGTIRLAARIYLQKGFP--------IKDDFLEQSERLFGAKPVKLTGKQEEDLANIN 205

  Fly   140 NWVDNQTRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMS 204
            .||...|.|||:|.:|....|.: |::||||:|.|.|..||:|.||:|..|.:.::.:|.|:||.
Mouse   206 QWVKEATEGKIEDFLSELPDSTV-LLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMH 269

  Fly   205 LFQ-----------SFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVD-GLSELEKKIVG---F 254
            ...           ..:.||          .|::| ::|.::.:|...: .:||:...:..   :
Mouse   270 AVSYPLRWFLLEQPEIQVAH----------FPFKN-NMSFVVVMPTYFEWNVSEVLANLTWDTLY 323

  Fly   255 KPKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEV 319
            .|.|.:....:.|||..::....|...|..:|:|:.|: ..|.:.:.| .|:.|..|.|::.:|:
Mouse   324 HPSLQERPTKVWLPKLHLQQQLDLVATLSQLGLQELFQ-GPDLRGISE-QNLVVSSVQHQSTMEL 386

  Fly   320 NEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRETI---YFQGHFVKPN 374
            :|.|.||||||::...|.|:   ||   |..:.||.:.|.: :||   .|.|....||
Mouse   387 SEAGVEAAAATSVAMNRMSL---SS---FTVNRPFLFFIME-DTIGVPLFVGSVRNPN 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	110/377 (29%)
Serpinf2	NP_032904.1	alpha2AP	82..433	CDD:239008	110/377 (29%)
Serpinf2	NP_032904.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..491
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010