Protein Alignment Spn28F and SERPINA12

DIOPT Version :9

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001291390.1
• Gene: SERPINA12 / 145264
• HGNCID: 18359
• Length: 414
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 94/359 - (26%)
• Similarity: 187/359 - (52%)
• Gaps: 20/359 - (5%)

  Fly    25 LAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMR---NVLKLPDDKKEVAAKYKDLLSKLEG 86
            ||..|...|:..||||:..|.||..:||:..|..|::   |..|:|:  |::...:..::.:|..
Human    63 LAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPE--KDLHEGFHYIIHELTQ 125

  Fly    87 REKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIVNNWVDNQTRGKIK 151
            :.:...||:.|.::::::.|....:.:..|:.:.||....:..:...|...:|:::..:|.|||.
Human   126 KTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKIN 190

  Fly   152 DLVSSNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQSFRAAHDSE 216
            :|:.:.|...: :::.|.|:|:.:|:::|:|.:||:.:|.:....||.|.||.....::..:|.:
Human   191 NLIENIDPGTV-MLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDK 254

  Fly   217 LGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKI-----VGFKPKLSKMDVTLRLPKFKIEFFA 276
            |...|:|:||: .:::.:..|||: ..|..|||.:     ..:|..||:..|.:.:|:..:....
Human   255 LSCTILEIPYQ-KNITAIFILPDE-GKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTF 317

  Fly   277 QLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAATALLFVRYSMPM 341
            .|.|.|..:|:...||:..|...:..:.::.|.:.:|||.::::|.|.|.||.|.    ..::||
Human   318 DLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTG----AQTLPM 378

  Fly   342 PSSQMVFNADHPFAYVIRDRE--TIYFQGHFVKP 373
             .:.:|...|.|:..:|...:  ::.|.|..|.|
Human   379 -ETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	92/354 (26%)
SERPINA12	NP_001291390.1	serpinA12_vaspin	40..411	CDD:381026	93/357 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010