DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28F and Serpina6

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_031644.1	Gene:	Serpina6 / 12401	MGIID:	88278	Length:	397	Species:	Mus musculus

Alignment Length:	398	Identity:	107/398 - (26%)
Similarity:	192/398 - (48%)	Gaps:	56/398 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HLCLLLLATS---------------------VSCRFADDFYQLLAKENAANNLISSPLSVEIALS 46
            :.||..|.||                     .:..||.:.|:.|...|:..|.:.||:|:.:||:
Mouse     6 YTCLFWLCTSGLWTTQAVTDEDSSSHRDLAPTNVDFAFNLYKRLVALNSDKNTLISPVSISMALA 70

  Fly    47 MAYMGARAKTAQEMR----NVLKLPDDKKEVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQL 107
            |..:..|..| |.:.    |:.|:  .:.|:...::.|.|.|:..:....:::.|.:::.:..:|
Mouse    71 MLSLSTRGST-QYLENLGFNMSKM--SEAEIHQGFQYLNSLLQQSDTGLEMNMGNVMFLLQNLKL 132

  Fly   108 VPSYNQMVKDSFMA------EAEAIDI--VDPNKASSIVNNWVDNQTRGKIKDLVSSNDMSKMEL 164
                    ||||:|      |:||:.|  .|..||...:||.|.|:|:|||:.:||..| |...|
Mouse   133 --------KDSFLADTKHYYESEALTIPSKDWTKAGEQINNHVKNKTQGKIEHVVSDLD-SSATL 188

  Fly   165 IVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQSFRAAHDSELGAKIIELPYRNS 229
            |::|.|:.||.|:..|:|:.|::.:|.|::..:|.|.||....:.....||.:..:::::.|..:
Mouse   189 ILINYIFLKGIWKLPFSPENTREEDFYVNETSTVKVPMMVQSGNISYFRDSAIPCQMVQMNYVGN 253

  Fly   230 SLSMLIFLPD--QVDG-LSELEKKIVGFKPKLS-KMDVTLRLPKFKIEFFAQLNKVLVAMGIQDA 290
            ..:.:| |||  |:|. ::.|.:..:....||. ...:.|.:|||.:.....|..||..:||:|.
Mouse   254 GTTFII-LPDQGQMDTVVAALNRDTIDRWGKLMIPRQMNLYIPKFSMSDTYDLQDVLADVGIKDL 317

  Fly   291 FEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFA 355
            |...:||.|..:::.:.: .|:|||.::::|.....||...     ..:.:||.......:.||.
Mouse   318 FTNQSDFADTTKDTPLTL-TVLHKAMLQLDEGNVLPAATNG-----PPVHLPSESFTLKYNRPFI 376

  Fly   356 YVIRDRET 363
            ::..|:.|
Mouse   377 FLAFDKYT 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	102/366 (28%)
Serpina6	NP_031644.1	SERPIN	43..396	CDD:214513	100/361 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020