DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28F and Serpinb5

DIOPT Version :9

Sequence 1:NP_524957.2 Gene:Spn28F / 49807 FlyBaseID:FBgn0028987 Length:375 Species:Drosophila melanogaster
Sequence 2:NP_476449.2 Gene:Serpinb5 / 116589 RGDID:69342 Length:375 Species:Rattus norvegicus


Alignment Length:391 Identity:119/391 - (30%)
Similarity:203/391 - (51%) Gaps:43/391 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LLLATSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKK 71
            |.||.|.   ||.:.::.|.::..|.|::.||:.:..:||:|.:||:..||.|:..||.. ::.|
  Rat     4 LRLANSA---FAVELFKQLCEKEPAGNILFSPICLSTSLSLAQVGAKGDTANEIGQVLHF-ENVK 64

  Fly    72 EVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDP-NKAS 135
            :|...::.:.|.:.......:|.|..|:|::|...|...:....|..:..|.|.:|..|. .:..
  Rat    65 DVPFGFQTITSDVNKLSSFYSLKLIKRLYIDKSLNLSTEFISSTKRPYANELETVDFKDKLEETK 129

  Fly   136 SIVNNWVDNQTRGKIKDLVSSNDMS-KMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVP 199
            ..:|:.:...|.|..:|::..|.:| :.:::|:||.||.|:|..||....||:..||::...:.|
  Rat   130 GQINSSIKELTDGHFEDILPENSISDQTKILVVNAAYFVGKWMKKFPESETKECPFRINKTDTKP 194

  Fly   200 VEMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLP----DQVDGLSELEKKIVGFKPK--- 257
            |:||:|..:|...:..::..||||||::|..|||||.||    |:..||.::||::   .|:   
  Rat   195 VQMMNLEATFCLGNIDDINCKIIELPFQNKHLSMLIVLPKDVEDESTGLEKIEKQL---NPETLL 256

  Fly   258 -------LSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAF-EKSADFKDLVENSNVHVKKVIHK 314
                   ::...|.|.|||||:|........|.::|::..| |.::||..:.|...|.|..|||:
  Rat   257 QWTNPSTMANAKVKLSLPKFKVEKMIDPKASLESLGLKSLFNESTSDFSGMSETKGVSVSNVIHR 321

  Fly   315 AFIEVNEEGAEAAAATALLFVRYSMPMPSSQMV-----FNADHPFAYVIRDRET--IYFQGHFVK 372
            ..:|:.|:|.:            |:.:|.|:::     |.|||||.:::|..:|  |.|.|.|..
  Rat   322 VCLEITEDGGD------------SIEVPGSRILQHKDEFKADHPFLFIVRHNKTRNIVFLGKFSS 374

  Fly   373 P 373
            |
  Rat   375 P 375

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28FNP_524957.2 SERPIN 14..370 CDD:238101 113/379 (30%)
Serpinb5NP_476449.2 serpinB5_maspin 1..375 CDD:381013 118/389 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X28
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.930

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