Protein Alignment Spn38F and SERPINB7

DIOPT Version :10

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_003775.1
• Gene: SERPINB7 / 8710
• HGNCID: 13902
• Length: 380
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 100/375 - (26%)
• Similarity: 192/375 - (51%)
• Gaps: 26/375 - (6%)

  Fly    12 SVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKL---------P 67
            :.:..|..:|::.:.....:.|:..|.||:..||:|..:||:..:..::..:|.:         .
Human     6 AANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGYGNSS 70

  Fly    68 DDKKEVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAIS-ANNP 131
            :.:..:.::.|.:.|.:........||:.|.::....:....:|.:..:..:.|:.|.:. .|:.
Human    71 NSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFTNHL 135

  Fly   132 KITASIVNKWVDTQTSGKIRDLVMPSDV-ANLVLVILNAIYFKGQWQKKFNTEQTKSDFHISDQK 195
            :.|...:||||:.:|.|||::::....: ::.|:|::||:||||:||..|...:| .:.|....|
Human   136 EDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSET-INCHFKSPK 199

  Fly   196 --SVPVQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPDKVDGLPELEKK------MVG 252
              ...|.||...|.|.:|...:....::||.| |..::|.:.||:  :.|.|:|.|      |..
Human   200 CSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYVLLPE--NDLSEIENKLTFQNLMEW 261

  Fly   253 FTP-KLININVHLRLPKFKIEFSARLEQVLIAMGIQDAF-KTSADFNDLVANSGAHVGGVVHKAF 315
            ..| ::.:..|.:..|:||||.:..::|.|.|:|::|.| ::.||.:.:.:....::..::||::
Human   262 TNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKSY 326

  Fly   316 LEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIRDAENIYFQG 365
            :||.|||:||.|||......|.:....: |..:|||.:|||..:.|.|.|
Human   327 IEVTEEGTEATAATGSNIVEKQLPQSTL-FRADHPFLFVIRKDDIILFSG 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	serpin42Dd-like_insects	12..370	CDD:381070	100/375 (27%)
SERPINB7	NP_003775.1	serpinB7_megsin	1..380	CDD:381032	100/375 (27%)