Protein Alignment Spn38F and SERPINB7

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001035237.1
• Gene: SERPINB7 / 8710
• HGNCID: 13902
• Length: 380
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 100/375 - (26%)
• Similarity: 192/375 - (51%)
• Gaps: 26/375 - (6%)

  Fly    12 SVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKL---------P 67
            :.:..|..:|::.:.....:.|:..|.||:..||:|..:||:..:..::..:|.:         .
Human     6 AANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGYGNSS 70

  Fly    68 DDKKEVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAIS-ANNP 131
            :.:..:.::.|.:.|.:........||:.|.::....:....:|.:..:..:.|:.|.:. .|:.
Human    71 NSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFTNHL 135

  Fly   132 KITASIVNKWVDTQTSGKIRDLVMPSDV-ANLVLVILNAIYFKGQWQKKFNTEQTKSDFHISDQK 195
            :.|...:||||:.:|.|||::::....: ::.|:|::||:||||:||..|...:| .:.|....|
Human   136 EDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSET-INCHFKSPK 199

  Fly   196 --SVPVQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPDKVDGLPELEKK------MVG 252
              ...|.||...|.|.:|...:....::||.| |..::|.:.||:  :.|.|:|.|      |..
Human   200 CSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYVLLPE--NDLSEIENKLTFQNLMEW 261

  Fly   253 FTP-KLININVHLRLPKFKIEFSARLEQVLIAMGIQDAF-KTSADFNDLVANSGAHVGGVVHKAF 315
            ..| ::.:..|.:..|:||||.:..::|.|.|:|::|.| ::.||.:.:.:....::..::||::
Human   262 TNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKSY 326

  Fly   316 LEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIRDAENIYFQG 365
            :||.|||:||.|||......|.:....: |..:|||.:|||..:.|.|.|
Human   327 IEVTEEGTEATAATGSNIVEKQLPQSTL-FRADHPFLFVIRKDDIILFSG 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	100/373 (27%)
SERPINB7	NP_001035237.1	serpinB7_megsin	1..380	CDD:381032	100/375 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.980