Protein Alignment Spn38F and Serpinb12

DIOPT Version :10

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_082247.1
• Gene: Serpinb12 / 71869
• MGIID: 1919119
• Length: 423
• Species: Mus musculus
• Alignment Length: 422
• Identity: 129/422 - (30%)
• Similarity: 224/422 - (53%)
• Gaps: 65/422 - (15%)

  Fly    11 TSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVL----------K 65
            |:.:.:|..|.::.::|::|.||:...|||:..|..:..:||||.:|.::.:.|          |
Mouse     5 TAANNKFCFDFFREISKDDAHKNIFVCPLSLSAAFGMVRLGARGDSAHQIDEALHFNELSKDEHK 69

  Fly    66 LPDD----------------KKEVAAK-----------------FKDLLSKLEGRESVAILSLAN 97
            .|:|                :|:.:|.                 |..|||:::..:|...||:||
Mouse    70 EPNDPSPQSESKASDSSLEGQKQTSASQDQQGESTNDHQLLGCHFGKLLSRIDRDKSYYTLSMAN 134

  Fly    98 RIYVNNKFKLVPEYNQMVKDSFKAEAEAIS-ANNPKITASIVNKWVDTQTSGKIRDLVMPSDVAN 161
            |:|...:|.:..||:..|.:.|....|::. ..:.:.:...:|.||::|:.|||::|.....:.|
Mouse   135 RLYGEQEFPICSEYSDDVTEFFHTTVESVDFQKDSEKSRQEINFWVESQSQGKIKELFGKEAIDN 199

  Fly   162 -LVLVILNAIYFKGQWQKKFNTEQT-KSDFHISDQKSVPVQMMSLVRPFGVSYDRELGANVIELP 224
             .|||::||:|||.:|:::||:|.| .:.|.:::.:...|:||:....|.:.:..||.|.::|:.
Mouse   200 STVLVLVNAVYFKAKWEREFNSENTVDASFCLNENEKKTVKMMNQKGKFRIGFIDELQAQILEMK 264

  Fly   225 YRNSNLSMVIFLP----DKVDGLPELEKKMVGFTPKLI------NIN---VHLRLPKFKIEFSAR 276
            |....|||::.||    |.|:.|.|||||:  ...||:      |::   |.:..|:|.:|.|..
Mouse   265 YAMGKLSMLVLLPSCSEDNVNSLQELEKKI--NHEKLLAWSSSENLSEKPVAISFPQFNLEDSYD 327

  Fly   277 LEQVLIAMGIQDAF-KTSADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRS 340
            |:.:|..|||:|.| :|.||...:..:...::..:|||.|:||:|.|::||||:.||...|::.|
Mouse   328 LKSILQDMGIKDVFDETKADLTGISKSPNLYLSKIVHKTFVEVDEMGTQAAAASGVVAAEKALPS 392

  Fly   341 PPMDFNVNHPFAYVIR--DAENIYFQGHFVNP 370
             .::||.||||.:.||  ..:::.|.|....|
Mouse   393 -WVEFNANHPFLFFIRHNPTQSLLFCGRVYCP 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	serpin42Dd-like_insects	12..370	CDD:381070	127/419 (30%)
Serpinb12	NP_082247.1	serpinB12_yukopin	1..423	CDD:381037	128/420 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..106		5/42 (12%)