DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn38F and Serpine3

DIOPT Version :9

Sequence 1:	NP_524956.2	Gene:	Spn38F / 49806	FlyBaseID:	FBgn0028986	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_006252257.2	Gene:	Serpine3 / 691375	RGDID:	1585042	Length:	413	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	97/400 - (24%)
Similarity:	168/400 - (42%)	Gaps:	54/400 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLLLATSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDK 70
            |.||.|    .|...|||..|.|....|.:.||.||.::|.:....|||.|..::.:.|......
  Rat    28 LWLLKT----EFALHLYQSAAAETNGTNFVISPASVSLSLEILQFAARGNTGWQLAEALGYTVQD 88

  Fly    71 KEVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITA 135
            ..|......:...|........:.||..:::.....|.|.:.:.|.....:..|....:.|..|.
  Rat    89 PRVREFLHTVYITLHNSSQGIGMELACTLFMQTGTSLSPCFVEQVSRWANSSLELADFSEPNTTT 153

  Fly   136 SIVNKWVDTQTSGK--IRDLVMPSDVANLVLVILNAIYFKGQWQKKFNTEQTKSDFHISDQKSVP 198
            ...:|.....::|:  ...|...:...:..|.|::.:.|:..||::|:              ||.
  Rat   154 MEASKGTTRPSTGEGPGSPLWGRAGALSTQLSIVSTMTFQSSWQQRFS--------------SVA 204

  Fly   199 VQMMSLVRPFG-------------VSYDRELGA-----NVIELPYRNSNLSMVIFLP-DKVDGLP 244
            :|.:......|             |||.:...|     :|:||.|.....|:::.|| ||...|.
  Rat   205 LQPLPFTCAHGLVLQVPAMHQVAEVSYGQFQDAAGHKVDVLELLYLGRVASLLLVLPQDKGTPLD 269

  Fly   245 ELEKKMVG-----FTPKLININVHLRLPKFKIEFSARLEQVLIAMGIQDAF-KTSADFNDLVANS 303
            .:|..:..     :|.:|....:.:.||:|:|:....|:.:|.:.||.|.| ...|:...:....
  Rat   270 HIEPHLTARVIHLWTTRLKRARMDVFLPRFRIQNQFDLKSILRSWGITDLFDPLKANLKGISGRD 334

  Fly   304 GAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIRDAENIYFQ---- 364
            |.:|..|.|||.:|::|||:::.|||||:...:| |:|.  |..:.||.:::|:...:..:
  Rat   335 GFYVSEVTHKAKMELSEEGTKSCAATAVLLLRRS-RTPA--FKADRPFIFLLREHNTVAVRITHG 396

  Fly   365 --GHFVNPEL 372
              .:|:|.:|
  Rat   397 KVANFLNFQL 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	91/388 (23%)
Serpine3	XP_006252257.2	serpin	20..400	CDD:422956	94/392 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110