Protein Alignment Spn38F and Serpinb1a

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_079705.2
• Gene: Serpinb1a / 66222
• MGIID: 1913472
• Length: 379
• Species: Mus musculus
• Alignment Length: 377
• Identity: 130/377 - (34%)
• Similarity: 212/377 - (56%)
• Gaps: 19/377 - (5%)

  Fly    11 TSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKKEVAA 75
            :|.:..|..:|:|.|.:.:...|:..||.|:..||::..:||:|.||.::...... |..:::.:
Mouse     5 SSANTLFALELFQTLNESSPTGNIFFSPFSISSALAMVILGAKGSTAAQLSKTFHF-DSVEDIHS 68

  Fly    76 KFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITA-SIVN 139
            :|:.|.:::..|.:...|.||||:|....:..:|||....:..:.|:...:...:....| ..:|
Mouse    69 RFQSLNAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASTQKMYGADLAPVDFLHASEDARKEIN 133

  Fly   140 KWVDTQTSGKIRDLVMPSDVANLV-LVILNAIYFKGQWQKKFNTEQ-TKSDFHISDQKSVPVQMM 202
            :||..||.|||.:|:....|.::. ||::|||||||.|::||.||. |.:.|.:|.:.:..|:||
Mouse   134 QWVKGQTEGKIPELLSVGVVDSMTKLVLVNAIYFKGMWEEKFMTEDTTDAPFRLSKKDTKTVKMM 198

  Fly   203 SLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLP----DKVDGLPELEK-----KMVGFTPK-- 256
            ...:.|...|..:|...|:|:||:...|||||.||    |:..||.::||     |::.:|.:
Mouse   199 YQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPKDIEDESTGLKKIEKQITLEKLLEWTKREN 263

  Fly   257 LININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTS-ADFNDLVANSGAHVGGVVHKAFLEVNE 320
            |..|:||::||:||||.|..|...|..:|:||.|.:| ||.:.:..:....:..:|||:|:||||
Mouse   264 LEFIDVHVKLPRFKIEESYTLNSNLGRLGVQDLFSSSKADLSGMSGSRDLFISKIVHKSFVEVNE 328

  Fly   321 EGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIR--DAENIYFQGHFVNP 370
            ||:||||||..:..: .:..|..:|.|:|||.:.||  ...|:.|.|...:|
Mouse   329 EGTEAAAATGGIATF-CMLLPEEEFTVDHPFIFFIRHNPTSNVLFLGRVCSP 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	128/372 (34%)
Serpinb1a	NP_079705.2	serpinB1_LEI	1..379	CDD:381028	129/375 (34%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	351..379		10/27 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		otm44055
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10598
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.960