Protein Alignment Spn38F and SERPINE3

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 102/419 - (24%)
• Similarity: 171/419 - (40%)
• Gaps: 90/419 - (21%)

  Fly    11 TSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKKEVA- 74
            |.:...|...|||.:|....:.|.:.||..|.:.|.:...||.|.|.|::.|.|......|.|.
Human    27 TLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVKD 91

  Fly    75 ---AKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITAS 136
               |.:..|.:..:|.|    :.||..::|.....|.|.:.:.|.....:..|....:.|..||.
Human    92 FLHAVYATLPTSSQGTE----MELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNSTAI 152

  Fly   137 IVNKWVDTQTSGKIRDLVMPSD-----------VANLVLVILNAIYFKGQWQKKFNTEQTKSDFH 190
            ..::....:|:|.     .||:           .|...||:::.:.|:|.|:|:|::..|:
Human   153 QTSEGASRETAGG-----GPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSSTDTQ---- 208

  Fly   191 ISDQKSVPVQMMSLVRPFGVSYDREL----------------------GANVIELPYRNSNLSMV 233
                          :.||..:|...|                      ...|:||||..|.:|:.
Human   209 --------------ILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLF 259

  Fly   234 IFLP-DKVDGLPELEKKMVG-----FTPKLININVHLRLPKFKIEFSARLEQVLIAMGIQDAF-K 291
            :.|| ||...|..:|..:..     :|..|....:.:.||:|:|:....|:.:|.:.|:.|.| .
Human   260 LVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDP 324

  Fly   292 TSADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIR 356
            ..|:...:....|.:|...:|||.:||.|||::|:.|||::...:| |.|  .|..:.||.|.:|
Human   325 LKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRS-RIP--IFKADRPFIYFLR 386

  Fly   357 DAE---NIYF-------------QGHFVN 369
            :..   .::|             :|.||:
Human   387 EPNTGITVFFDRIQIIYQCLSSNKGSFVH 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	101/416 (24%)
SERPINE3	NP_001094790.1	SERPIN	31..399	CDD:238101	98/397 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		7/35 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020