DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn38F and serpine3

DIOPT Version :9

Sequence 1:	NP_524956.2	Gene:	Spn38F / 49806	FlyBaseID:	FBgn0028986	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001116709.1	Gene:	serpine3 / 556612	ZFINID:	ZDB-GENE-050309-223	Length:	417	Species:	Danio rerio

Alignment Length:	413	Identity:	125/413 - (30%)
Similarity:	200/413 - (48%)	Gaps:	54/413 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YLCLLL-----LATSV-SCRFTD-------DLYQLLAKENADKNLITSPLSVEIALSLAYMGARG 54
            ::||.|     :|.|| |..|:|       .|||.|.:.....|||.||.||.:.|.|..:||||
Zfish    10 FICLWLVDLCHVANSVLSSSFSDLHTQFGISLYQTLTETENKSNLIVSPASVSLCLGLLQLGARG 74

  Fly    55 KTAQEMRDVLKLPDDKKEVAAKFKDLLSKLEG---RESVAI-LSLANRIYVNNKFKLVPEYNQMV 115
            .|..::...|..  |..:|  :.:::||:.:|   ..|..: |.|||.:::....||:||:.|..
Zfish    75 NTLVQLEGTLGY--DVNDV--RVQNILSRPQGDLANSSEGLRLQLANALFIQTGVKLLPEFTQHA 135

  Fly   116 KDSFKAEAEAISANNPKITASIVNKWVDTQ---------------TSGKIRDLVMPSDVANLVLV 165
            .........:::.:||..|.|.:.:|...|               :||:..:......:  |.:.
Zfish   136 LGWGNTSLLSVNFSNPNHTHSRLQQWAHYQSKADDHLQTREELHHSSGEEEEATRQDHL--LYMA 198

  Fly   166 ILNAIYFKGQWQKKF-NTEQTKSDFHISDQKSVPVQMMSLVRPFGVSYDR---ELGANVIELPYR 226
            :::.:.|.|.|||:| .||.....|..||..:|.|.||.......:.:.|   |....|:||||.
Zfish   199 LVSTLVFHGAWQKQFLFTETQNLPFTFSDGSTVKVPMMYQSSEVNIGHFRLPSEQEYTVLELPYL 263

  Fly   227 NSNLSMVIFLP-DKVDGLPELEKKM----VG-FTPKLININVHLRLPKFKIEFSARLEQVLIAMG 285
            :.:|.:::.|| |:...|.:|||::    || :...|....:.:.||:||::....|:.||.::|
Zfish   264 DHSLRLLVALPSDRKTPLSQLEKQITARAVGLWDTGLRRTKMDIFLPRFKMQSKINLKPVLQSLG 328

  Fly   286 IQDAFKTS-ADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNH 349
            :.|.|..| |||..:....|..|....|:|.:||.|.|::||:|||:|...:| ||..  |..:.
Zfish   329 VSDIFSPSAADFRGISDTDGIFVSEAFHEARIEVTEAGTKAASATAMVLLKRS-RSAV--FKADR 390

  Fly   350 PFAYVIRDAE--NIYFQGHFVNP 370
            ||.:::|...  ::.|.|..|||
Zfish   391 PFLFILRQISTGSLLFIGRVVNP 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	117/394 (30%)
serpine3	NP_001116709.1	Serpin	35..413	CDD:278507	114/386 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110