DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn38F and serpinh1a

DIOPT Version :9

Sequence 1:	NP_524956.2	Gene:	Spn38F / 49806	FlyBaseID:	FBgn0028986	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001103844.1	Gene:	serpinh1a / 555328	ZFINID:	ZDB-GENE-080219-21	Length:	403	Species:	Danio rerio

Alignment Length:	400	Identity:	96/400 - (24%)
Similarity:	190/400 - (47%)	Gaps:	43/400 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LCLLLLAT--------SVSCRFTD-------DLYQLLAKENADKNLITSPLSVEIALSLAYMGAR 53
            |.|.||||        |::....|       :|||.:||:...:|::.||:.|..:|.|..:|.:
Zfish     7 LLLCLLATVSANKTLSSIATTLADNSATLAFNLYQNMAKDKDIENILISPVVVASSLGLVALGGK 71

  Fly    54 GKTAQEMRDVLKLPDDKKE-VAAKFKDLLSKLEGRESVAIL-SLANRIYVNNKFKLVPEYNQMVK 116
            ..||.:::.||.....|.| :.:...:||:::...::..:. .::||.|..:....|.::.:..|
Zfish    72 SNTASQVKTVLSAASVKDEQLHSGLSELLTEVSNPKARNVTWKISNRFYGPSSVSFVDDFLKSSK 136

  Fly   117 DSFKAEAEAISANNPKITASIVNKWVDTQTSGKIRDL---VMPSDVANLVLVILNAIYFKGQWQK 178
            ..:..:...|:..:.:.....:|.|....|.||:.::   |..:|.|    :|:||:::|..|.:
Zfish   137 KHYNYDHSKINFRDKRSAVKAINDWASKSTDGKLPEVTKDVEKTDGA----MIINAMFYKPHWNE 197

  Fly   179 KFNTEQTKS-DFHISDQKSVPVQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPDKVDG 242
            :|:.:...: .|.:....:|.|.||.....:|...|......|:|:|..:...|:|:.:|..|:.
Zfish   198 QFHHKMVDNRGFLVHRSFTVSVPMMHRTGIYGFLDDTTNKLLVLEMPLAHKMSSLVLIMPYHVES 262

  Fly   243 LPELEKKMVGFTPKLINI--------NVHLRLPKFKIEFSARLEQVLIAMGIQDAF-KTSADFND 298
            |..:||.:   |.:.:|.        .|.:.|||..:|.|..|::.|..:|:.:|. |..||.::
Zfish   263 LERVEKLL---TRQQLNTWVSAMEQKAVAISLPKVSMEVSHNLQKHLAELGLTEAVDKAKADLSN 324

  Fly   299 LVANSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIRD--AENI 361
            :......::..|.|.:.:|.:.||:....:   :|....:::|.: |..:|||.::::|  ..:|
Zfish   325 ISGKKDLYLSNVFHASAMEWDTEGNPPDTS---IFGTDQLKNPKL-FYADHPFVFLVKDNKTNSI 385

  Fly   362 YFQGHFVNPE 371
            .|.|..:.|:
Zfish   386 LFMGRLIRPK 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	88/379 (23%)
serpinh1a	NP_001103844.1	SERPIN	26..391	CDD:294093	88/375 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920