Protein Alignment Spn38F and SERPINI2

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001012303.2
• Gene: SERPINI2 / 5276
• HGNCID: 8945
• Length: 405
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 118/392 - (30%)
• Similarity: 202/392 - (51%)
• Gaps: 31/392 - (7%)

  Fly     4 LCLLLLATSVS-C------RFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMR 61
            |.||...:..| |      .|..||||.::..:.| |:|.|||.:.:.|.:..:||:||..|::|
Human     9 LLLLFFGSQASRCSAQKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIR 72

  Fly    62 DVLKLPDDKKEVAA-----KFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKA 121
            ..||    ::|.:|     ..|...|.:..::.....:|||.:|:...|.:..:|....|:.|::
Human    73 QTLK----QQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQS 133

  Fly   122 EAEAISANNPKITASIVNKWVDTQTSGKIRDLVMPSDVANLV-LVILNAIYFKGQWQKKFNTEQT 185
            ..:.:...:.|..|.:::.||:.:|.|||:|:....:...|. ||::|||||||.|::||..|.|
Human   134 AIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDT 198

  Fly   186 K-SDFHISDQKSVPVQMM-SLVR-PFGVSYDRELGANVIELPYRNSNLSMVIFLPDKVDGLPELE 247
            : .:|...:..:|.:.|| :|:| .:|...:..|...|:||.|:....|::|.||.:...:.|:|
Human   199 QLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEEVE 263

  Fly   248 K-----KMVGFTPKLININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHV 307
            |     :::.:..::....|.:.||:||:|.....:.||.::.|.:.|....|.:.:..:|..:|
Human   264 KLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGITDSSEVYV 328

  Fly   308 GGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRS-PPMDFNVNHPFAYVIR--DAENIYFQGHFVN 369
            ..|..|.|.|:||:|||||.:|.:  ....|.| ....|..||||.::::  ..|:|.|.|...|
Human   329 SQVTQKVFFEINEDGSEAATSTGI--HIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTN 391

  Fly   370 PE 371
            |:
Human   392 PD 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	113/379 (30%)
SERPINI2	NP_001012303.2	serpinI2_pancpin	23..392	CDD:381042	111/375 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930