Protein Alignment Spn38F and SERPINB13

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 127/399 - (31%)
• Similarity: 218/399 - (54%)
• Gaps: 44/399 - (11%)

  Fly    12 SVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKK--EVA 74
            :||.|...||::.|.|.| |.|:..||:.:..|:.:..:|.||.||.::.:|.....:.|  .:.
Human     6 AVSTRLGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIK 69

  Fly    75 AKFKDLLS-KLEGRE---SVAI-------------------LSLANRIYVNNKFKLVPEYNQMVK 116
            |:.|:::. |.||:|   :.|:                   |::.||::....:..:.:|...|:
Human    70 AEEKEVVRIKAEGKEIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVE 134

  Fly   117 DSFKAEAEAIS-ANNPKITASIVNKWVDTQTSGKIRDLVMPSDVANLV-LVILNAIYFKGQWQKK 179
            ..:.|..|.:. .|....:...:|.||:::|:.||:||.....:::.. ||::|.:||||||.::
Human   135 KYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 199

  Fly   180 FNTEQTKSD-FHISDQKSVPVQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPDKVDGL 243
            |..|.||.: |.::...|..||||:....|..::..:|.|.::.:||:|::|||.:.||:.:|||
Human   200 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGL 264

  Fly   244 PEL-----EKKMVGFTP--KLININVHLRLPKFKIEFSARLEQVLIAMGIQDAF-KTSADFNDLV 300
            .::     .:|:|.:|.  .:....|:|.||:|::|....||.||.|||:.||| :..||::.:.
Human   265 EKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMS 329

  Fly   301 ANSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPMDFNV--NHPFAYVIR--DAENI 361
            :.||.:....:|.:|:.|.|||:||||||.:.|   ::.|.|...||  ||||.:.||  ::.:|
Human   330 SGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGF---TVTSAPGHENVHCNHPFLFFIRHNESNSI 391

  Fly   362 YFQGHFVNP 370
            .|.|.|.:|
Human   392 LFFGRFSSP 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	125/395 (32%)
SERPINB13	NP_001294852.1	SERPIN	4..400	CDD:294093	126/397 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.980