Protein Alignment Spn38F and SERPINB10

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_005015.1
• Gene: SERPINB10 / 5273
• HGNCID: 8942
• Length: 397
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 133/406 - (32%)
• Similarity: 217/406 - (53%)
• Gaps: 56/406 - (13%)

  Fly     9 LATSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKL------- 66
            ||||:: :|..:|.:.||:....||:..|..|:..:|::.|:||:|.||.:|..||:.
Human     4 LATSIN-QFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVK 67

  Fly    67 --PDDKK------------EVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKD 117
              |:.:|            |:.:.|:.|:|::.......:|..||.||....:....:|.:.:|.
Human    68 CDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLEDMKT 132

  Fly   118 SFKAEAEAISANNPKITAS-----IVNKWVDTQTSGKIRDLVMPSDVANLV--LVILNAIYFKGQ 175
            .|.||.:.::.    :.||     .:|.||:.||.|||::| :|.|..:..  ::::||:||||.
Human   133 YFGAEPQPVNF----VEASDQIRKDINSWVERQTEGKIQNL-LPDDSVDSTTRMILVNALYFKGI 192

  Fly   176 WQKKF---NTEQTKSDFHISDQKSVPVQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLP 237
            |:.:|   ||  |:..|.|::..|.|||||.:.:...:.:..:..|..::|.|::.:||::|.||
Human   193 WEHQFLVQNT--TEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRDLSLLILLP 255

  Fly   238 DKVDGLPELEKKMVGFTPKLIN----------INVHLRLPKFKIEFSARLEQVLIAMGIQDAFKT 292
            :.::||.:|||   ..|.:.:|          ..|.|.|||||:|.|..|:..|.:||:.|||..
Human   256 EDINGLEQLEK---AITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQ 317

  Fly   293 S-ADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIR 356
            | |||:.:.:.....:..|.||||:|:||:|:||||.:......: ||.|.::||.||||.:.||
Human   318 SKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIR-IRVPSIEFNANHPFLFFIR 381

  Fly   357 --DAENIYFQGHFVNP 370
              ....|.|.|...:|
Human   382 HNKTNTILFYGRLCSP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	128/399 (32%)
SERPINB10	NP_005015.1	PAI-2	4..397	CDD:239013	132/404 (33%)
		Nuclear localization signal	74..77		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.830