Protein Alignment Spn38F and SERPINB8

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001353127.1
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Alignment Length: 366
• Identity: 130/366 - (35%)
• Similarity: 201/366 - (54%)
• Gaps: 14/366 - (3%)

  Fly    17 FTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKKEVAAKFKDLL 81
            |...|:::|.:|:..:|:..||:|:..||::.:|||:|.||.:|...|.|..| .::...|:.||
Human    11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKD-GDIHRGFQSLL 74

  Fly    82 SKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAIS-ANNPKITASIVNKWVDTQ 145
            |::....:..:|..|||::.......:|::.:..:..::||.|.:| |.:.:.....:|.||..:
Human    75 SEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEK 139

  Fly   146 TSGKIRDLVMPSDVANLV-LVILNAIYFKGQWQKKFNTEQTKSDFHISDQKSVPVQMMSLVRPFG 209
            |.|||.:::....|..|. ||::|||||||:|.::|:.:.|:.....::::...||||.....|.
Human   140 TEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKTVQMMFKEAKFK 204

  Fly   210 VSYDRELGANVIELPYRNSNLSMVIFLPDKVDGLPELEK-----KMVGFT--PKLININVHLRLP 267
            :.|..|:...|:||||....|||||.|||....|..:||     |...:|  .||....|.:.||
Human   205 MGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLP 269

  Fly   268 KFKIEFSARLEQVLIAMGIQDAF-KTSADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAV 331
            :.|:|.|..||..|..:|:.||| :..|||:.:.......:..|.||.|:||||||:||||||||
Human   270 RLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAV 334

  Fly   332 VFRYKSIRSPPMDFNVNHPFAYVIRDAEN--IYFQGHFVNP 370
            |...:..|..|. |..:|||.:.||..:.  |.|.|.|.:|
Human   335 VRNSRCSRMEPR-FCADHPFLFFIRHHKTNCILFCGRFSSP 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	129/364 (35%)
SERPINB8	NP_001353127.1	SERPIN	4..374	CDD:320777	129/364 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930