Protein Alignment Spn38F and SERPINB5

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 113/382 - (29%)
• Similarity: 194/382 - (50%)
• Gaps: 28/382 - (7%)

  Fly     7 LLLATSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKK 71
            |.||.|.   |..||::.|.::....|::.||:.:..:||||.:||:|.||.|:..||.. ::.|
Human     4 LQLANSA---FAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF-ENVK 64

  Fly    72 EVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNP-KITA 135
            :|...|:.:.|.:....|...|.|..|:||:....|..|:....|..:..|.|.:...:. :.|.
Human    65 DVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETK 129

  Fly   136 SIVNKWVDTQTSGKIRDLVMPSDVANLV-LVILNAIYFKGQWQKKFNTEQTKS-DFHISDQKSVP 198
            ..:|..:...|.|...:::..:.|.:.. ::::||.||.|:|.|||:..:||. .|.::...:.|
Human   130 GQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKP 194

  Fly   199 VQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLP----DKVDGLPELEKKMVGFT----- 254
            ||||::...|.:.....:...:||||::|.:|||.|.||    |:..||.::||::...:
Human   195 VQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWT 259

  Fly   255 --PKLININVHLRLPKFKIEFSARLEQVLIAMGIQDAF-KTSADFNDLVANSGAHVGGVVHKAFL 316
              ..:.|..|.|.:||||:|.....:..|..:|::..| :.::||:.:....|..:..|:||..|
Human   260 NPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCL 324

  Fly   317 EVNEEGSEAAAAT-AVVFRYKSIRSPPMDFNVNHPFAYVIR--DAENIYFQGHFVNP 370
            |:.|:|.::.... |.:.::|.      :.|.:|||.|:||  ...||.|.|.|.:|
Human   325 EITEDGGDSIEVPGARILQHKD------ELNADHPFIYIIRHNKTRNIIFFGKFCSP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	108/373 (29%)
SERPINB5	NP_002630.2	maspin_like	4..375	CDD:239012	112/380 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930