Protein Alignment Spn38F and SERPINA1

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 105/367 - (28%)
• Similarity: 187/367 - (50%)
• Gaps: 21/367 - (5%)

  Fly    17 FTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVL-----KLPDDKKEVAAK 76
            |...||:.||.::...|:..||:|:..|.::..:|.:..|..|:.:.|     ::|:  .::...
Human    57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPE--AQIHEG 119

  Fly    77 FKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITASIVNKW 141
            |::||..|...:|...|:..|.::::...|||.::.:.||..:.:||..::..:.:.....:|.:
Human   120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDY 184

  Fly   142 VDTQTSGKIRDLVMPSDVANLVLVILNAIYFKGQWQKKFNTEQT-KSDFHISDQKSVPVQMMSLV 205
            |:..|.|||.|||...| .:.|..::|.|:|||:|::.|..:.| :.|||:....:|.|.||..:
Human   185 VEKGTQGKIVDLVKELD-RDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248

  Fly   206 RPFGVSYDRELGANVIELPYRNSNLSMVIFLPDKVDGLPELEKKMVG--FTPKLIN---INVHLR 265
            ..|.:.:.::|.:.|:.:.|. .|.:.:.||||: ..|..||.::..  .|..|.|   .:..|.
Human   249 GMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLH 311

  Fly   266 LPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATA 330
            |||..|..:..|:.||..:||...|...||.:.:...:...:...||||.|.::|:|:|||.|
Human   312 LPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGA-- 374

  Fly   331 VVFRYKSIRSPPMDFNVNHPFAYVI--RDAENIYFQGHFVNP 370
             :|......|.|.:...|.||.:::  ::.::..|.|..|||
Human   375 -MFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	103/365 (28%)
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	102/362 (28%)
		RCL	368..392		8/26 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010