Protein Alignment Spn38F and SERPINB2

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001137290.1
• Gene: SERPINB2 / 5055
• HGNCID: 8584
• Length: 415
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 124/431 - (28%)
• Similarity: 204/431 - (47%)
• Gaps: 77/431 - (17%)

  Fly     1 MKYLCLLLLATSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLK 65
            |:.||:      .:..|..:|::.|||.:..:||..||.|:...:::.|||:||.|..:|..||:
Human     1 MEDLCV------ANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQ 59

  Fly    66 L------------------------------PD--------DKKEVAAKFKDLLSKLEGRESVAI 92
            .                              ||        ||  :.:.|:.|.|.:.......:
Human    60 FNEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADK--IHSSFRSLSSAINASTGNYL 122

  Fly    93 LSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAIS----ANNPKITASIVNKWVDTQTSGKIRDL 153
            |...|:::.........||.::.:..:.:|.:|:.    |...:   ..:|.||.|||.|||.:|
Human   123 LESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEAR---KKINSWVKTQTKGKIPNL 184

  Fly   154 VMPSDV-ANLVLVILNAIYFKGQW----QKKFNTEQTKSDFHISDQKSVPVQMMSLVRPFGVSYD 213
            :....| .:..:|::||:||||:|    :||.|   ....|.::..:..|||||.|.....:.|.
Human   185 LPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLN---GLYPFRVNSAQRTPVQMMYLREKLNIGYI 246

  Fly   214 RELGANVIELPYRNSNLSMVIFLPDKV----DGLPELEK-----KMVGFT--PKLININVHLRLP 267
            .:|.|.::||||. .::||.:.|||::    .||..||.     |:..:|  .|:....|.:.:|
Human   247 EDLKAQILELPYA-GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310

  Fly   268 KFKIEFSARLEQVLIAMGIQDAF-KTSADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAV 331
            :||:|....|..:|.:||::||| |..|:|:.:...:...:..|.|:|.::|||||:||||.|..
Human   311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGG 375

  Fly   332 VFRYKSIRSPPMDFNVNHPFAYVI--RDAENIYFQGHFVNP 370
            |...::....| .|..:|||.::|  :....|.|.|.|.:|
Human   376 VMTGRTGHGGP-QFVADHPFLFLIMHKITNCILFFGRFSSP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	120/416 (29%)
SERPINB2	NP_001137290.1	PAI-2	4..415	CDD:239013	122/426 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930