Protein Alignment Spn38F and SERPINC1

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 125/428 - (29%)
• Similarity: 200/428 - (46%)
• Gaps: 77/428 - (17%)

  Fly    11 TSVSCRFTDDLYQLLA-KENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKKEVA 74
            :..:.||....||.|| .:|.:.|:..||||:..|.::..:||...|.|::.:|.|.....::.:
Human    84 SKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTS 148

  Fly    75 AKFKDLLSKLEGR------ESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAIS-ANNPK 132
            .:.....:||..|      :|..::| |||::.:........|..:.:..:.|:.:.:. ..|.:
Human   149 DQIHFFFAKLNCRLYRKANKSSKLVS-ANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAE 212

  Fly   133 ITASIVNKWVDTQTSGKIRDLVMPSDVAN--LVLVILNAIYFK---------------------- 173
            .:.:.:||||..:|.|:|.| |:||:..|  .|||::|.||||
Human   213 QSRAAINKWVSNKTEGRITD-VIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFF 276

  Fly   174 -------------------GQWQKKFNTEQTKSD-FHISDQKSVPVQMMSLVRPFGVSYDREL-G 217
                               |.|:.||:.|.|:.: |:.:|.:|....||.....|  .|.|.. |
Human   277 FKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKF--RYRRVAEG 339

  Fly   218 ANVIELPYRNSNLSMVIFLPDKVDGLPELEKKMVGFTPKLIN----------INVHLRLPKFKIE 272
            ..|:|||::..:::||:.||.....|.::||::   ||:::.          :.||  :|:|:||
Human   340 TQVLELPFKGDDITMVLILPKPEKSLAKVEKEL---TPEVLQEWLDELEEMMLVVH--MPRFRIE 399

  Fly   273 FSARLEQVLIAMGIQDAFK-TSADFNDLVA--NSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFR 334
            ....|::.|..||:.|.|. ..:....:||  ....:|....||||||||||||||||:||||..
Human   400 DGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIA 464

  Fly   335 YKSIRSPPMDFNVNHPFAYVIRDA--ENIYFQGHFVNP 370
            .:|:....:.|..|.||...||:.  ..|.|.|...||
Human   465 GRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	123/423 (29%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	125/428 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.940