Protein Alignment Spn38F and SERPINA2

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 103/387 - (26%)
• Similarity: 186/387 - (48%)
• Gaps: 40/387 - (10%)

  Fly     8 LLATSVSCRFTD---DLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKL--- 66
            |....:|...||   |||:.||..:...|::.:|.||.:|.::..:|.:..|..|:.:.|.:
Human    48 LACQKISYNVTDLAFDLYKELADLSQTSNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLT 112

  Fly    67 --PDDKKEVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISAN 129
              |:.|  :...|:.:|..|...::...|:..:.::||...|||..:.:..|..:.:||.:|:..
Human   113 ETPEAK--IHECFQQVLQALSRPDTRLQLTTGSSLFVNKSMKLVDTFLEDTKKLYHSEASSINFR 175

  Fly   130 NPKITASIVNKWVDTQTSGKIRDLV--MPSDVANLVLVILNAIYFKGQWQKKFNTEQTKSD-FHI 191
            :.:.....:|.:|:.:|..|:.|||  :..|.:   |.:::.|.|.|:|:.||..|....: ||:
Human   176 DTEEAKEQINNYVEKRTGRKVVDLVKHLKKDTS---LALVDYISFHGKWKDKFKAEHIMVEGFHV 237

  Fly   192 SDQKSVPVQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPDKVDGLPELEKKMVGFTPK 256
            .|:..:.|.|::.:..|.:..||||.:.|:...| ..|.:....|||. ..:.:||:|:.  ...
Human   238 DDKTIIRVPMINHLGRFDIHRDRELSSWVLAQHY-VGNATAFFILPDP-KKMWQLEEKLT--YSH 298

  Fly   257 LINI-------NVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGVVHKA 314
            |.||       :::|..||..|..:.:|::||..:||...|...||.:.:...:...:...||.|
Human   299 LENIQRAFDIRSINLHFPKLSISGTYKLKRVLRNLGITKIFSNEADLSGVSQEAPLKLSKAVHVA 363

  Fly   315 FLEVNEEGSEAAAATAVV----FRYKSIRSPPMDFNVNHPFAYVIRDAENIY--FQGHFVNP 370
            .|.::|:|:||..|..:.    .:|:::.       .|.||..:|:|....:  |.|..|||
Human   364 VLTIDEKGTEATGAPHLEEKAWSKYQTVM-------FNRPFLVIIKDDITNFPLFIGKVVNP 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	100/379 (26%)
SERPINA2	NP_006211.2	SERPIN	62..418	CDD:214513	97/371 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010