DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn38F and Serpina11

DIOPT Version :9

Sequence 1:	NP_524956.2	Gene:	Spn38F / 49806	FlyBaseID:	FBgn0028986	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001008776.1	Gene:	Serpina11 / 362774	RGDID:	1359239	Length:	462	Species:	Rattus norvegicus

Alignment Length:	417	Identity:	97/417 - (23%)
Similarity:	183/417 - (43%)	Gaps:	65/417 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVL-----KLPDDK 70
            |.....|...||:.||:| ...|::.||:|:...::|..:||...|..::...|     :.|  .
  Rat    51 TPTITNFALRLYKQLAEE-IPGNILFSPVSLSSTVALLSLGAHADTQAQILQSLGFNLTETP--A 112

  Fly    71 KEVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITA 135
            .::...|:.||..|:.......|.|.:.::::.:.|....:....|:.:.|.|.:.:......|.
  Rat   113 ADIHRGFQSLLHTLDLPSPKLELKLGHSLFLDRQLKPQQRFLDSAKELYGALAFSANFTEAAATG 177

  Fly   136 SIVNKWVDTQTSGKIRDLVMPSDVANLVLVILNAIYFKGQWQKKFNTEQTK--SDFHISDQKSVP 198
            ..:|..|..||.|::.. .:|....:.::|:||.|:||.:|:..|:..||:  ..|.:..:..:.
  Rat   178 QQINDLVRKQTYGQVVG-CLPEFDRDTLMVLLNYIFFKAKWKHPFDRYQTRKQESFFVDQRLQLR 241

  Fly   199 VQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVI-------------------------FLP- 237
            :.||.........||:|....|:::.|..:.|.:::                         |||
  Rat   242 IPMMRQKEMHRFLYDQEASCTVLQIEYSGTALLLLVLPDPGKMQQVEAALQPETLRRWGQRFLPR 306

  Fly   238 --------------DKVDGLPE-----LEKKMVGFTPKLININVHLRLPKFKIEFSARLEQVLIA 283
                          |:|:..|:     |..|.:..|.....:::|  ||:|.:..:..||::|..
  Rat   307 KAQAGGAGNGGLHWDRVNEFPQNRVGKLSLKHLQMTQTWSLLDLH--LPRFSVSATYNLEEILPL 369

  Fly   284 MGIQDAFKTSADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIR---SPPMDF 345
            :|:...|...||.:.::......|..|.|||.:::||:|:|||||:.::.:..|:.   :|...|
  Rat   370 VGLSSLFDVEADLSGIMGQLNKTVSRVSHKAVVDMNEKGTEAAAASGLLSQPPSLNMTSAPHAHF 434

  Fly   346 NVNHPFAYVIRD--AENIYFQGHFVNP 370
              |.||..::.:  .:::.|.|..|||
  Rat   435 --NRPFLLLLWEVTTQSLLFLGKVVNP 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	94/412 (23%)
Serpina11	NP_001008776.1	alpha-1-antitrypsin_like	53..456	CDD:239011	93/410 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010