DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn38F and Serpina1f

DIOPT Version :9

Sequence 1:	NP_524956.2	Gene:	Spn38F / 49806	FlyBaseID:	FBgn0028986	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001101524.1	Gene:	Serpina1f / 314406	RGDID:	1307899	Length:	412	Species:	Rattus norvegicus

Alignment Length:	419	Identity:	86/419 - (20%)
Similarity:	190/419 - (45%)	Gaps:	74/419 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LCLLLLATSV--------------SCR--------FTDDLYQLLAKENADKNLITSPLSVEIALS 46
            ||.||..|..              .||        .:..|::.:|:.:.:.|::.||:.|..|:|
  Rat    16 LCCLLPITKTKYEDLYEDPNIDPFQCRKVALTISNISITLFKEMAQLSVNGNILFSPIRVIAAIS 80

  Fly    47 LAYMGARGKTAQEMRDVLK-----LPDDKKEVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFK 106
            :..:||:|..::.:.::|:     ||:  .|:...|:.||..:...|.::.|...:.::::....
  Rat    81 MLSLGAKGNESKRILEILRLNKTGLPE--AEIHKCFRYLLRAIHQPEQLSPLKSGSGVFIHQDLT 143

  Fly   107 LVPEYNQMVKDSFKAEAEAISANNPKITASIVNKWVDTQTSGKIRDLV--MPSDVANLVLVILNA 169
            .|.::.:.||:.:.::..:|:..:.:...:.:|.::.|:::.:|:::|  :.:|.   .:.::|.
  Rat   144 PVDKFVEGVKNLYHSDIVSINFTDCRRAKTQINNYMMTKSNKEIKNIVKNLENDT---YMAVVNY 205

  Fly   170 IYFKGQWQKKFNTE-----QTKSDFHISDQKSVPVQMMSLVRPFGVSYDRELGANVIELPYRNSN 229
            |.    |..|.|::     ..:.|:|:....::.|.|:.:|....:....:|.:.|:......||
  Rat   206 II----WNAKINSDFGCRSVKQKDYHLEQGMTIKVPMIHIVDLNHLFRVEDLSSTVLVFTLLASN 266

  Fly   230 LSMVIFLPDKVDGLPELEKKMVGFTPKLININ-------VHLRLPKFKIEFSARLEQVLIAMGIQ 287
            .:....:|| :..:.::|:::.  .|....:.       |:|..|:..:..:..:|.::..:||.
  Rat   267 FTTYFIIPD-IGQMQKVEQRLT--YPHFRRMRRQSNLRMVNLETPELSLSETHDVESMMNLLGIT 328

  Fly   288 DAFKTSADFNDLVANSGAHVGGVVHKAF-------LEVNEEGSEAAAATAVVFRYKSIRSPPMDF 345
            ..|.     ||  |||.|.:...:.|:|       |.::::||:...:|.    :|:..|..:.:
  Rat   329 YVFN-----ND--ANSSAVMNDTLQKSFKMVSKVKLTIDDKGSKPGRSTC----FKNDGSVDVGY 382

  Fly   346 -NVNHPFAYVIRDAEN--IYFQGHFVNPE 371
             ..|.||...|:|..|  ..|.|..|||:
  Rat   383 VQFNRPFLIFIKDPTNDVPLFLGRVVNPK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	79/392 (20%)
Serpina1f	NP_001101524.1	serpin	47..410	CDD:422956	77/385 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010