DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn38F and Serpinb13

DIOPT Version :9

Sequence 1:	NP_524956.2	Gene:	Spn38F / 49806	FlyBaseID:	FBgn0028986	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001100638.1	Gene:	Serpinb13 / 304690	RGDID:	1304661	Length:	389	Species:	Rattus norvegicus

Alignment Length:	387	Identity:	123/387 - (31%)
Similarity:	211/387 - (54%)	Gaps:	29/387 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVL---------KL 66
            ::.:..|..||::.|.| .:|.|:..|||.:..|:.:..:|.:|.||.|::.||         :|
  Rat     5 STATTHFLFDLFKELNK-TSDGNVFFSPLGISTAIGMILLGTQGATASELQKVLYSEQGTGSSRL 68

  Fly    67 PDDKKEVAA------KFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEA 125
            ..::||:..      :|:.||:::........|.::||:|....:..:.:|...|:..:.|..|.
  Rat    69 KSEEKEIEKTEEIHHQFQKLLTEISKPTKDYDLIISNRLYGERTYLFLQKYIDYVEKYYHASLEP 133

  Fly   126 IS-ANNPKITASIVNKWVDTQTSGKIRDLVMPSDV-ANLVLVILNAIYFKGQWQKKFNTEQTK-S 187
            :. .|....:...:|.||::||:.|::||.....: ::..||::|.:||||.|.::|..|.|| .
  Rat   134 VDFVNAADESRKKINSWVESQTNEKVKDLFPEGSLNSSTKLVLINTVYFKGLWDREFKKEHTKEE 198

  Fly   188 DFHISDQKSVPVQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPDKVDGLPEL-----E 247
            ||.::...|.|||||:....|..:...:|.|.::.:||:||:.||.:.||:.:|||.::     .
  Rat   199 DFWLNKNISKPVQMMAQCSSFSFTLLEDLQAKIVGIPYKNSDFSMFVLLPNDIDGLEKIIDKLSP 263

  Fly   248 KKMVGFTP--KLININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGV 310
            :|:|.:|.  :|....|.||||:.|:|.:..|:..|.|:||..||...||::.:.|:||......
  Rat   264 EKLVEWTSPGQLKQRKVDLRLPRLKVEETYDLQPTLEAVGIHSAFSEHADYSGMSAHSGLQTQNF 328

  Fly   311 VHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVI--RDAENIYFQGHFVNP 370
            :|::||.|.|||.||.|.|.|.|:..|..|..: .:.||||.:.:  |::::|.|.|.|.:|
  Rat   329 LHRSFLVVTEEGVEATAGTGVGFKVLSAASCEL-VHCNHPFLFFVRHRESDSILFFGRFSSP 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	122/382 (32%)
Serpinb13	NP_001100638.1	SERPIN	4..389	CDD:294093	122/385 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		otm46144
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930