DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn38F and Serpina3m

DIOPT Version :9

Sequence 1:	NP_524956.2	Gene:	Spn38F / 49806	FlyBaseID:	FBgn0028986	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001257911.1	Gene:	Serpina3m / 299276	RGDID:	735068	Length:	419	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	125/382 - (32%)
Similarity:	204/382 - (53%)	Gaps:	29/382 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLATSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKL---PDD 69
            |...|::..|...||::||.:|.|||::.||||:..||::..:||:|.|.:|:.:||:.   ...
  Rat    45 LTLESINTDFAFSLYKMLALKNPDKNVVFSPLSISAALAIVSLGAKGNTLEEILEVLRFNLTESY 109

  Fly    70 KKEVAAKFKDLLSKL-EGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKI 133
            :.::...|..||.:| :..:.|.|:: .|.::::...:::.|:.:..:..::.||.......|::
  Rat   110 ETDIHQGFGHLLQRLSQPGDQVKIIT-GNALFIDKNLQVLAEFQEKTRALYQVEAFTADFQQPRV 173

  Fly   134 TASIVNKWVDTQTSGKIRDLVMP-SDVANLVLVILNAIYFKGQWQKKFNTEQT-KSDFHISDQKS 196
            |..::|.:|..||.|||::||.. .:..::|||  |.:.|:|:|:..|:.:.| :|:|::.:::|
  Rat   174 TEKLINDYVRNQTQGKIQELVSGLKERTSMVLV--NYLLFRGKWKVPFDPDYTFESEFYVDEKRS 236

  Fly   197 VPVQMM---SLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPDK-----VDG--LPE-LEKKM 250
            |.|.||   .|..|:  ..|.||..:|:||.| ..|.|.:..||||     |:.  .|| |:|..
  Rat   237 VKVSMMKIEELTTPY--FRDEELSCSVLELKY-TGNSSALFILPDKGRMQQVEASLQPETLKKWK 298

  Fly   251 VGFTPKLININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGVVHKAF 315
            ....|:.|:   .|.||:..|.....||:||..:||:|.|...||.:.:.......|..||||..
  Rat   299 DSLRPRKID---ELYLPRLSISTDYSLEEVLPELGIRDVFSQQADLSRITGAKDLSVSQVVHKVV 360

  Fly   316 LEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVI--RDAENIYFQGHFVNP 370
            |:|||.|:||||||......:|.| |||....|.||...:  ...:.|.|....:||
  Rat   361 LDVNETGTEAAAATGANLVPRSGR-PPMIVWFNRPFLIAVSHTHGQTILFMAKVINP 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	121/374 (32%)
Serpina3m	NP_001257911.1	SERPIN	56..416	CDD:214513	120/369 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010