DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn38F and Serpinf2

DIOPT Version :9

Sequence 1:	NP_524956.2	Gene:	Spn38F / 49806	FlyBaseID:	FBgn0028986	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001011892.1	Gene:	Serpinf2 / 287527	RGDID:	1306692	Length:	491	Species:	Rattus norvegicus

Alignment Length:	379	Identity:	120/379 - (31%)
Similarity:	184/379 - (48%)	Gaps:	54/379 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKKEVAAKFKDLL 81
            ||.||:.|:|:.:...||:.|||||.:|||...:|||.:|.:.::.||.:     .:.:....||
  Rat    89 FTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGARNQTLENLQRVLHM-----NMGSCIPHLL 148

  Fly    82 SKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNP-KITA------SIVN 139
            |......:...:.||.|||:...|.        :||.|..::|.:....| |:|.      ..:|
  Rat   149 SHFCQNLNPGTIRLAARIYLQKGFP--------IKDDFLEQSEKLFGAKPVKLTGRQEEDLMNIN 205

  Fly   140 KWVDTQTSGKIRDLV--MPSDVANLVLVILNAIYFKGQWQKKFNTEQTKSD-FHISDQKSVPVQM 201
            |||...|.|||.|.:  :|.   |.||::||||:|.|.|:.||:...|:.| ||:.:|.:|||.|
  Rat   206 KWVKEATEGKIEDFLSELPD---NTVLLLLNAIHFHGFWRTKFDPSLTQKDSFHLDEQFTVPVAM 267

  Fly   202 MSLVRPFGVSYD------RELGANVIELPYRNSNLSMVIFLP-----DKVDGLPELEKKMVGFTP 255
            |     ...||.      .:....|...|::| |:|.|:.:|     :..:.|..|....: :.|
  Rat   268 M-----HAQSYPLRWFLLEQPEIQVAHFPFQN-NMSFVVIMPTYFGWNVSEVLANLTWDTL-YQP 325

  Fly   256 KLININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGVVHKAFLEVNE 320
            .:......:||||..:|....|...|..:|:||.|: |.|... :::....|..|.|::.:|::|
  Rat   326 SMREKPTKVRLPKLHLEQHLDLVATLSKLGLQDLFQ-SPDLRG-ISDQSLVVSSVQHQSTMELSE 388

  Fly   321 EGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIRDAENI---YFQGHFVNPE 371
            .|.||||||:......|:.|    |.:|.||.:.|.: |.|   .|.|...||:
  Rat   389 AGVEAAAATSTAMTRMSLSS----FFLNRPFIFFIME-ETIGIPLFVGSVRNPD 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	118/376 (31%)
Serpinf2	NP_001011892.1	alpha2AP	82..433	CDD:239008	118/373 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010