Protein Alignment Spn38F and SERPINA11

DIOPT Version :10

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 99/381 - (25%)
• Similarity: 188/381 - (49%)
• Gaps: 33/381 - (8%)

  Fly    11 TSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVL-----KLPDDK 70
            |.....|...||:.||.: |..|:..||:|:...|:|..:||:..|:..:.:.|     :.|:
Human    51 TPTITNFALRLYKELAAD-APGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPE-- 112

  Fly    71 KEVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITA 135
            .::...|:.||..|........|.:.|.::::.:.|....|...:|:.:.|.|.:.:..:...|.
Human   113 ADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTG 177

  Fly   136 SIVNKWVDTQTSGKIRDLVMPSDVANLVLVILNAIYFKGQWQKKFNTEQT--KSDFHISDQKSVP 198
            ..:|.::..||.|::.| .:|....:..:|:.|.|:||.:|:..|:..||  :..|.:.::.|:.
Human   178 RQINDYLRRQTYGQVVD-CLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQ 241

  Fly   199 VQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPD-----KVDGL--PELEKKMVG--FT 254
            |.||.........||::|...|:::.||.:.|:::: |||     :|:..  |:..:|. |  ..
Human   242 VPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV-LPDPGKMKQVEAALQPQTLRKW-GQLLL 304

  Fly   255 PKLININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGVVHKAFLEVN 319
            |.|::    |.||:|.|..:..||.:|..:|:.:.....|||:.:.......:..|.|||.::::
Human   305 PSLLD----LHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMS 365

  Fly   320 EEGSEAAAATAVVFRYKSIRS---PPMDFNVNHPFAYVIRD--AENIYFQGHFVNP 370
            |:|:||.||:.::.:..|:.:   |...|  |.||..::.:  .:::.|.|..|||
Human   366 EKGTEAGAASGLLSQPPSLNTMSDPHAHF--NRPFLLLLWEVTTQSLLFLGKVVNP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	serpin42Dd-like_insects	12..370	CDD:381070	96/378 (25%)
SERPINA11	NP_001073920.1	serpinA11	50..422	CDD:381025	99/381 (26%)