Protein Alignment Spn38F and SERPINA12

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001291390.1
• Gene: SERPINA12 / 145264
• HGNCID: 18359
• Length: 414
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 93/369 - (25%)
• Similarity: 184/369 - (49%)
• Gaps: 35/369 - (9%)

  Fly    21 LYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMR---DVLKLPDDKKEVAAKFKDLLS 82
            |.:.||..|..:|:..||||:..|.|:..:||:..|..|::   :..|:|:  |::...|..::.
Human    59 LLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPE--KDLHEGFHYIIH 121

  Fly    83 KLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITASIVNKWVDTQTS 147
            :|..:.....||:.|.::::.:.:...::.:..|:.:.||....:..|.::....:|.::..:|.
Human   122 ELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTH 186

  Fly   148 GKIRDLVMPSDVANLVLVILNAIYFKGQWQKKFNTEQTK-SDFHISDQKSVPVQMMSLVRPFGVS 211
            |||.:|:...| ...|:::.|.|:|:.:|:.:|:...|| .||.:....||.|.||.....:.|.
Human   187 GKINNLIENID-PGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVG 250

  Fly   212 YDRELGANVIELPYRNSNLSMVIFLPDKVDGLPELEKKM---------VGFTPKLININVHLRLP 267
            ||.:|...::|:||: .|::.:..|||: ..|..|||.:         ...:.::::::|    |
Human   251 YDDKLSCTILEIPYQ-KNITAIFILPDE-GKLKHLEKGLQVDTFSRWKTLLSRRVVDVSV----P 309

  Fly   268 KFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAVV 332
            :..:..:..|::.|..:|:...|:...|...:..:....||..||||.|:::|.|:|.||.|..
Human   310 RLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGA- 373

  Fly   333 FRYKSIRSPPMD----FNVNHPFAYVIRDAE--NIYFQGHFVNP 370
                  ::.||:    ..::.|:..:|...:  ::.|.|..|||
Human   374 ------QTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	91/367 (25%)
SERPINA12	NP_001291390.1	serpinA12_vaspin	40..411	CDD:381026	91/367 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010