Protein Alignment Spn38F and SERPINA3

DIOPT Version :9

• Sequence 1: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001076.2
• Gene: SERPINA3 / 12
• HGNCID: 16
• Length: 423
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 122/375 - (32%)
• Similarity: 189/375 - (50%)
• Gaps: 19/375 - (5%)

  Fly    12 SVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKL---PDDKKEV 73
            |.:..|...||:.|..:..|||:|.||||:..||:...:||...|..|:...||.   ...:.|:
Human    51 SANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEI 115

  Fly    74 AAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITASIV 138
            ...|:.||..|........||:.|.::|..:..|:..:.:..|..:.:||.|....:......::
Human   116 HQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI 180

  Fly   139 NKWVDTQTSGKIRDLVMPSDVANLVLVILNAIYFKGQWQKKFNTEQT-KSDFHISDQKSVPVQMM 202
            |.:|...|.|||.||:...| :..::|::|.|:||.:|:..|:.:.| :|.|::|.:|.|.|.||
Human   181 NDYVKNGTRGKITDLIKDLD-SQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMM 244

  Fly   203 SLVRPFGVSY--DRELGANVIELPYRNSNLSMVIFLPDKVDGLPELEKKMVGFTPKLININVHLR 265
            || ....:.|  |.||...|:||.| ..|.|.:..|||: |.:.|:|..::..|.|....::..|
Human   245 SL-HHLTIPYFRDEELSCTVVELKY-TGNASALFILPDQ-DKMEEVEAMLLPETLKRWRDSLEFR 306

  Fly   266 ------LPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGVVHKAFLEVNEEGSE 324
                  ||||.|.....|..:|:.:||::||.:.||.:.:.......|..|||||.|:|.|||:|
Human   307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTE 371

  Fly   325 AAAATAV-VFRYKSIRSPPMDFNVNHPFAYVI--RDAENIYFQGHFVNPE 371
            |:||||| :....::.........|.||..:|  .|.:||:|.....||:
Human   372 ASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPK 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	119/370 (32%)
SERPINA3	NP_001076.2	serpinA3_A1AC	40..421	CDD:381019	121/373 (32%)
		RCL	369..394		8/24 (33%)
		O-glycosylated at one site	381..389		0/7 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010