DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn38F and Serpinb5

DIOPT Version :9

Sequence 1:NP_524956.2 Gene:Spn38F / 49806 FlyBaseID:FBgn0028986 Length:372 Species:Drosophila melanogaster
Sequence 2:NP_476449.2 Gene:Serpinb5 / 116589 RGDID:69342 Length:375 Species:Rattus norvegicus


Alignment Length:385 Identity:112/385 - (29%)
Similarity:199/385 - (51%) Gaps:34/385 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LLLATSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKK 71
            |.||.|.   |..:|::.|.::....|::.||:.:..:||||.:||:|.||.|:..||.. ::.|
  Rat     4 LRLANSA---FAVELFKQLCEKEPAGNILFSPICLSTSLSLAQVGAKGDTANEIGQVLHF-ENVK 64

  Fly    72 EVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNP-KITA 135
            :|...|:.:.|.:....|...|.|..|:|::....|..|:....|..:..|.|.:...:. :.|.
  Rat    65 DVPFGFQTITSDVNKLSSFYSLKLIKRLYIDKSLNLSTEFISSTKRPYANELETVDFKDKLEETK 129

  Fly   136 SIVNKWVDTQTSGKIRDLVMPSDVANLV-LVILNAIYFKGQWQKKFNTEQTKS-DFHISDQKSVP 198
            ..:|..:...|.|...|::..:.:::.. ::::||.||.|:|.|||...:||. .|.|:...:.|
  Rat   130 GQINSSIKELTDGHFEDILPENSISDQTKILVVNAAYFVGKWMKKFPESETKECPFRINKTDTKP 194

  Fly   199 VQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLP----DKVDGLPELEKKMVGFTPK--- 256
            ||||:|...|.:....::...:||||::|.:|||:|.||    |:..||.::||::   .|:   
  Rat   195 VQMMNLEATFCLGNIDDINCKIIELPFQNKHLSMLIVLPKDVEDESTGLEKIEKQL---NPETLL 256

  Fly   257 -------LININVHLRLPKFKIEFSARLEQVLIAMGIQDAF-KTSADFNDLVANSGAHVGGVVHK 313
                   :.|..|.|.|||||:|.....:..|.::|::..| ::::||:.:....|..|..|:|:
  Rat   257 QWTNPSTMANAKVKLSLPKFKVEKMIDPKASLESLGLKSLFNESTSDFSGMSETKGVSVSNVIHR 321

  Fly   314 AFLEVNEEGSEAAAAT-AVVFRYKSIRSPPMDFNVNHPFAYVIR--DAENIYFQGHFVNP 370
            ..||:.|:|.::.... :.:.::|.      :|..:|||.:::|  ...||.|.|.|.:|
  Rat   322 VCLEITEDGGDSIEVPGSRILQHKD------EFKADHPFLFIVRHNKTRNIVFLGKFSSP 375

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn38FNP_524956.2 Serpin 14..370 CDD:278507 107/376 (28%)
Serpinb5NP_476449.2 serpinB5_maspin 1..375 CDD:381013 111/383 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm46144
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X28
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
65.930

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