DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn38F and serpini1

DIOPT Version :9

Sequence 1:	NP_524956.2	Gene:	Spn38F / 49806	FlyBaseID:	FBgn0028986	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_031757359.1	Gene:	serpini1 / 100144746	XenbaseID:	XB-GENE-948443	Length:	428	Species:	Xenopus tropicalis

Alignment Length:	404	Identity:	140/404 - (34%)
Similarity:	211/404 - (52%)	Gaps:	39/404 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKYLCLLLL--------ATSVS----CRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGAR 53
            |.:|.||.|        .|||.    ..|:..:|..|.....|:|:|.||||..|||.:..:|||
Frog    19 MHHLSLLALIVMQALVFGTSVHDETVNEFSIKVYHKLRATIEDENIIFSPLSTAIALGMVELGAR 83

  Fly    54 GKTAQEMRDVLKLPDDKKEVAAKF---KDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMV 115
            |.:.:|:|.||..  ||.:...:|   |||.:.|..:|...:||:||.:|:.|.|.:..::.|::
Frog    84 GSSLKEIRHVLGY--DKLKNGEEFSLLKDLSNMLTAQEKHYVLSIANSLYLQNGFHISDKFIQLM 146

  Fly   116 KDSFKAEAEAISANNPKITASIVNKWVDTQTSGKIRDLVMPSDVANLV-LVILNAIYFKGQWQKK 179
            |..||||.|.:..:.....|:.:|.||:..|:.:|||||...|..||. ||::||:||||.|:.:
Frog   147 KKYFKAEVENVDFSQGSTVANHINMWVENHTNNRIRDLVTADDFTNLTKLVLVNAMYFKGNWKSQ 211

  Fly   180 FNTEQTKS-DFHISDQKSVPVQMMSLVRPFGVSYDREL--GAN-------VIELPYRNSNLSMVI 234
            |..|.|:: .|...|:..|.:.||.....|   |..|.  |:|       |:||||....:|::|
Frog   212 FRPENTRTFSFTKDDESEVQIPMMYQKGEF---YYGEFTDGSNEAGGVYQVLELPYEGDEISLII 273

  Fly   235 FLPDKVDGLPELEKKMVG-----FTPKLININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTSA 294
            .|..:...|..||..:..     :...:....|.:.||:||:|....|:.||:.:||...|...|
Frog   274 VLSRQEVPLATLEPLLKAPLIEEWANSVKKQKVEVYLPRFKVEEVVNLKDVLMQLGITKIFSGEA 338

  Fly   295 DFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIRDAE 359
            |.:.:..:....|...|||:|||||||||||||::.::...:.....|... |:|||.:|||:.:
Frog   339 DLSAVSDSKDLFVAKAVHKSFLEVNEEGSEAAASSGMIANSRMAVLYPQVI-VDHPFFFVIRNRK 402

  Fly   360 --NIYFQGHFVNPE 371
              ::.|.|..::||
Frog   403 TGSVLFMGRVMHPE 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn38F	NP_524956.2	Serpin	14..370	CDD:278507	130/380 (34%)
serpini1	XP_031757359.1	serpinI1_NSP	41..412	CDD:381005	130/376 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010