DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Da and SERPIN1

DIOPT Version :9

Sequence 1:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001320925.1	Gene:	SERPIN1 / 841182	AraportID:	AT1G47710	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	409	Identity:	137/409 - (33%)
Similarity:	207/409 - (50%)	Gaps:	37/409 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 PFPPVHTADVTMADAAHQEFARRLALFSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENE 86
            |.||. ..||..:.:...:.:..||...|....:.|      |::|||.||....::...|:...
plant    22 PQPPA-KMDVRESISLQNQVSMNLAKHVITTVSQNS------NVIFSPASINVVLSIIAAGSAGA 79

  Fly    87 TATQLDQGLGLASSDPEQIAHSFHQ--VLAAYQDSQI-----LRIANKIFVMDGYQLRQEFDQLL 144
            |..|:...|..:|:|.   .:||..  |.|...|...     |.:||..::......:..|.|||
plant    80 TKDQILSFLKFSSTDQ---LNSFSSEIVSAVLADGSANGGPKLSVANGAWIDKSLSFKPSFKQLL 141

  Fly   145 SKQFLSAAQSVDF-SKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQH 208
            ...:.:|:...|| ||.|:..|.:|:|.|:.||.||.:::|....:|.::|:..||::|||||..
plant   142 EDSYKAASNQADFQSKAVEVIAEVNSWAEKETNGLITEVLPEGSADSMTKLIFANALYFKGTWNE 206

  Fly   209 QFAKHLTRPDTFH-LDGERTVQVPMMSLKERFRYADLPALDAM-ALELPYKDS----DLSMLIVL 267
            :|.:.||:...|| |||.: |..|.|:.|:: :|  :.|.|.. .|.|||...    ..||...|
plant   207 KFDESLTQEGEFHLLDGNK-VTAPFMTSKKK-QY--VSAYDGFKVLGLPYLQGQDKRQFSMYFYL 267

  Fly   268 PNTKTGLPALEEKLRLTTLSQITQSLYETKVAL---KLPRFKAEFQVELSEVFQKLGMSRMFSDQ 329
            |:...||..|.:|: ::|...:...:...:|.:   |:|:||..|..:.|.|.:.||::..||.:
plant   268 PDANNGLSDLLDKI-VSTPGFLDNHIPRRQVKVREFKIPKFKFSFGFDASNVLKGLGLTSPFSGE 331

  Fly   330 AEFGKMLQSPE---PLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPF 391
            ....:|::|||   .|.||.|.|||.|||||||||||||:. .|.:.|.::..|:.|:|.|||||
plant   332 EGLTEMVESPEMGKNLCVSNIFHKACIEVNEEGTEAAAASA-GVIKLRGLLMEEDEIDFVADHPF 395

  Fly   392 TYVLVHQ-KDLPLFWGSVV 409
            ..|:... ..:.||.|.||
plant   396 LLVVTENITGVVLFIGQVV 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	130/383 (34%)
SERPIN1	NP_001320925.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
OMA	1	1.010	-	-		QHG57242
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1112
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.970