Protein Alignment Spn42Da and Serpina12

DIOPT Version :9

• Sequence 1: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 422
• Identity: 110/422 - (26%)
• Similarity: 205/422 - (48%)
• Gaps: 47/422 - (11%)

  Fly     4 RLVPCGCWLLPLL---GLAL-FPFPPVHTADVTMADAAHQEFARRLAL----FSINVYGKLSGQK 60
            |::..|.:|..||   ||.. ...|.::.:.|.:.:...::.||:||.    |...:..:|:...
Mouse     3 RMLDLGLFLAGLLTVKGLLQDRDAPDMYDSPVRVQEWRGKKDARQLARHNMEFGFKLLQRLASNS 67

  Fly    61 PGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQIAHSFHQVL----AAYQDSQI 121
            |..||..||.||.|..:|..|||:|.|..::.:|..........:..:||.:|    ...:|::
Mouse    68 PQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSNWDVHAAFHYLLHKLNQETEDTK- 131

  Fly   122 LRIANKIFVMDGYQLRQEFDQLLSKQ--FLSAAQSV--------DFSKNVQAAATINNWVEQRTN 176
            :.:.|.:|:          ||.|..|  ||:.|::|        :|.........||.::.|:|:
Mouse   132 MNLGNALFM----------DQKLRPQQRFLNLAKNVYDADMVLTNFQDLENTQKDINRYISQKTH 186

  Fly   177 HLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRY 241
            ..||::|.:  ::..:.::|.|.|:|:|.||::|....|:.:.|.::..:||:||||..:..:..
Mouse   187 SRIKNMVKS--IDPGTVMILTNYIYFRGRWQYEFDPKQTKEEEFFIEKGKTVKVPMMFQRGLYDM 249

  Fly   242 ADLPALDAMALELPYKDSDLSMLIVLP-NTKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRF 305
            |....|....||:||: .:::...||| |.|  |..||:.|:....::....|.:..|.:.:|:.
Mouse   250 AYDSQLSCTILEIPYR-GNITATFVLPDNGK--LKLLEQGLQADIFAKWKSLLSKRVVDVWVPKL 311

  Fly   306 KAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAV 370
            :......:.:|..:||:|::|.:..:..: :.|...|||...:|||.::::|:|.|.||.:|...
Mouse   312 RISSTYNMKKVLSRLGISKIFEENGDLTR-ISSHRSLKVGEAVHKAELKMDEKGMEGAAGSGAQT 375

  Fly   371 RRKRAIMSPEEPIEFFADHPFTYVLVHQKDLP 402
                  :..|.|.....|.|| .:::::..:|
Mouse   376 ------LPMETPRHMKLDRPF-LMMIYENFMP 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	99/377 (26%)
Serpina12	NP_080811.1	alpha-1-antitrypsin_like	51..408	CDD:239011	97/374 (26%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		6/23 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010