DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Da and serpinf2a

DIOPT Version :9

Sequence 1:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_688797.1	Gene:	serpinf2a / 560308	ZFINID:	ZDB-GENE-060822-1	Length:	457	Species:	Danio rerio

Alignment Length:	404	Identity:	111/404 - (27%)
Similarity:	193/404 - (47%)	Gaps:	74/404 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LALFSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQIAHSF 109
            :|...:.:..||.......||:.||.|:....|...|||.|.|..:|     |.....:::.| |
Zfish    47 VAKLGLTLLEKLQPGSEQPNIIISPLSVSLALAELALGARNNTEEKL-----LEVLHAKELPH-F 105

  Fly   110 HQVLAAYQD---SQILRIANKIFVMDGYQLRQEF-DQLLSKQFLSAAQSVDFSKNVQAAATINNW 170
            |:.|:..|:   ::.:::|::::::.||.:..:| |:.|:.....:||       :.:...:|.|
Zfish   106 HETLSCLQEHLTAKAVKMASRLYLVPGYTVNPDFVDRALNLYKSESAQ-------LTSIEDVNRW 163

  Fly   171 VEQRTNHLIKDL---VPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPM 232
            ||:.||..|.:.   :|.:|:     |:|:|||||||.||.:|....|:.:.||:|.:.:|:|.|
Zfish   164 VEETTNGQITNFMSSLPPNVV-----LMLINAIHFKGEWQSRFNSKYTKENIFHIDRKTSVKVDM 223

  Fly   233 MSLKERFRYADLPALD----AMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQSL 293
            |...:   |.....:|    .....||:: .::|:|:::|           :|:...||.:...|
Zfish   224 MMGSQ---YPLSMFVDRTDGTQVARLPFR-GNMSLLVIMP-----------RLQHENLSNVAAKL 273

  Fly   294 ----------YETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQ--SPEPLKVSA 346
                      .|..:.:.||:||.|::.:|.:....:|:..:|:     |..|.  :|.||.||.
Zfish   274 NISDMYARFPRERSMHVTLPKFKLEYKQDLRQALTSMGLGFLFT-----GPDLSRIAPGPLVVSG 333

  Fly   347 IIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFA-DHPFTYVLVHQKD-LPLFWGSVV 409
            :.|.:.:|::|||.||:|||...:.|         .|.||: :.||.:.||.... .|||.|.|.
Zfish   334 VQHASNMELSEEGAEASAATSFTLVR---------TISFFSVNMPFIFALVDDTSYTPLFLGIVT 389

  Fly   410 RLEENTFASSEHDE 423
              ..|..|.:|..:
Zfish   390 --NPNPGAKTEQSD 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	107/387 (28%)
serpinf2a	XP_688797.1	SERPIN	54..388	CDD:294093	106/380 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010