DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Da and serpine3

DIOPT Version :9

Sequence 1:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001116709.1	Gene:	serpine3 / 556612	ZFINID:	ZDB-GENE-050309-223	Length:	417	Species:	Danio rerio

Alignment Length:	422	Identity:	129/422 - (30%)
Similarity:	202/422 - (47%)	Gaps:	47/422 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 WLLPLLGLALFPFPPVHTADVTMADAAHQEFARRLALFSINVYGKLSGQKPGENIVFSPFSIQTC 75
            ||:.|          .|.|:..::.:    |:.....|.|::|..|:..:...|::.||.|:..|
Zfish    14 WLVDL----------CHVANSVLSSS----FSDLHTQFGISLYQTLTETENKSNLIVSPASVSLC 64

  Fly    76 AAMARLGAENETATQLDQGLGLASSD--PEQIAHSFHQVLAAYQDSQILRIANKIFVMDGYQLRQ 138
            ..:.:|||...|..||:..||...:|  .:.|.......||...:...|::||.:|:..|.:|..
Zfish    65 LGLLQLGARGNTLVQLEGTLGYDVNDVRVQNILSRPQGDLANSSEGLRLQLANALFIQTGVKLLP 129

  Fly   139 EFDQLLSKQFLSAAQSVDFSKNVQAAATINNWVEQRT---NHL--IKDLVPADVLNSESR----- 193
            ||.|.......::..||:||......:.:..|...::   :||  .::|..:.....|:.
Zfish   130 EFTQHALGWGNTSLLSVNFSNPNHTHSRLQQWAHYQSKADDHLQTREELHHSSGEEEEATRQDHL 194

  Fly   194 --LVLVNAIHFKGTWQHQFAKHLTR--PDTFHLDGERTVQVPMM--SLKERFRYADLPA-LDAMA 251
              :.||:.:.|.|.||.||....|:  |.||. ||. ||:||||  |.:....:..||: .:...
Zfish   195 LYMALVSTLVFHGAWQKQFLFTETQNLPFTFS-DGS-TVKVPMMYQSSEVNIGHFRLPSEQEYTV 257

  Fly   252 LELPYKDSDLSMLIVLP-NTKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSE 315
            |||||.|..|.:|:.|| :.||.|..||:::....:......|..||:.:.|||||.:.::.|..
Zfish   258 LELPYLDHSLRLLVALPSDRKTPLSQLEKQITARAVGLWDTGLRRTKMDIFLPRFKMQSKINLKP 322

  Fly   316 VFQKLGMSRMFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMA-VRRKRAIMSP 379
            |.|.||:|.:||..|...:.:...:.:.||...|:|.|||.|.||:||:||.|. ::|.|:.:
Zfish   323 VLQSLGVSDIFSPSAADFRGISDTDGIFVSEAFHEARIEVTEAGTKAASATAMVLLKRSRSAV-- 385

  Fly   380 EEPIEFFADHPFTYVL--VHQKDLPLFWGSVV 409
                 |.||.||.::|  :....| ||.|.||
Zfish   386 -----FKADRPFLFILRQISTGSL-LFIGRVV 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	121/385 (31%)
serpine3	NP_001116709.1	Serpin	35..413	CDD:278507	123/387 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020