Protein Alignment Spn42Da and SERPINI2

DIOPT Version :9

• Sequence 1: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001012303.2
• Gene: SERPINI2 / 5276
• HGNCID: 8945
• Length: 405
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 121/393 - (30%)
• Similarity: 208/393 - (52%)
• Gaps: 20/393 - (5%)

  Fly    42 ARRLALFSINVYGKLS-GQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQ- 104
            |::...|::::|.::| ..|  :||:|||..|.....|.:|||:.:...|:.|.|....:...:
Human    23 AQKNTEFAVDLYQEVSLSHK--DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEE 85

  Fly   105 --IAHSFHQVLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAAATI 167
              :..||...::..:......:||.:::.:|:.:::::.....:.|.||.:.|||......|..|
Human    86 FFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMI 150

  Fly   168 NNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPM 232
            :.|||::|:..|||:...:.....:||||||||:|||.|:.:|.|..|:...|......||::||
Human   151 STWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPM 215

  Fly   233 MS--LKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQ---S 292
            |.  |:.::.|....:|:...|||.||..:.|::|:||  ..|:. :||..:|.|..||.:   .
Human   216 MKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILP--AEGMD-IEEVEKLITAQQILKWLSE 277

  Fly   293 LYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNE 357
            :.|.:|.:.|||||.|.:|:..:|...|.::.:||...:...:..|.| :.||.:..|.|.|:||
Human   278 MQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGITDSSE-VYVSQVTQKVFFEINE 341

  Fly   358 EGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPFTYVLVHQ-KDLPLFWGSVVRLEENTFASSEH 421
            :|:|||.:||:.:   ..|||..:. :|.|:|||.:::.|. .:..||.|.|...:.......:.
Human   342 DGSEAATSTGIHI---PVIMSLAQS-QFIANHPFLFIMKHNPTESILFMGRVTNPDTQEIKGRDL 402

  Fly   422 DEL 424
            |.|
Human   403 DSL 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	117/372 (31%)
SERPINI2	NP_001012303.2	serpinI2_pancpin	23..392	CDD:381042	119/378 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	227	1.000	Domainoid score	I2508
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3439
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9820
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3483
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	11.010