Protein Alignment Spn42Da and SERPINA4

DIOPT Version :9

• Sequence 1: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 126/442 - (28%)
• Similarity: 197/442 - (44%)
• Gaps: 71/442 - (16%)

  Fly    12 LLPLLGLALFPFPPVHTA--DVTMADAAHQE------------FARRLALFSINVYGKLSGQKPG 62
            ||.|:||.......:|..  ..:.::::||:            .|...|.|:...|..::.:.||
Human    45 LLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPG 109

  Fly    63 ENIVFSPFSIQTCAAMARLGAENETATQLDQGLG-----LASSDPEQ-IAHSFHQVLAAYQDSQI 121
            :||.|||.||....||..|||.:.:.:|:.:|||     |:.||..: ..|..|.:.......:
Human   110 KNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLE- 173

  Fly   122 LRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSV--------DFSKNVQAAATINNWVEQRTNHL 178
            .|:.:.:|:  .:.|:     .|:| ||:...:|        :|...|.....||:.|::.|...
Human   174 TRVGSALFL--SHNLK-----FLAK-FLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGK 230

  Fly   179 IKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMM-SLKERFRYA 242
            |.|||  ..|..:..:||||.|:||..|:..|....|.|..|::|...||:|||| ..:|...|.
Human   231 IVDLV--SELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYL 293

  Fly   243 DLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQSL----YETKVALKLP 303
            ....|....|.:.|| .|.::..:||| :..:..:||.|....|.:....|    :..|:.|.||
Human   294 HDRYLPCSVLRMDYK-GDATVFFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLP 356

  Fly   304 RFKAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGM 368
            :|.......|.::..:||.:.:||..|:...:.:. :.|:.|...|||.::|:|.||||||||..
Human   357 KFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQ-QKLEASKSFHKATLDVDEAGTEAAAATSF 420

  Fly   369 AVRRKRAIMSPEEPIEFFA----------DHPFTYVLVH-QKDLPLFWGSVV 409
            |             |:||:          :.||..|:.. .....||.|.||
Human   421 A-------------IKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVV 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	115/392 (29%)
SERPINA4	NP_001275961.1	alpha-1-antitrypsin_like	91..458	CDD:239011	115/393 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020